Huang, Yu

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

Newman, J. C., Covarrubias, A. J., Zhao, M., Yu, X., Gut, P., Ng, C.-P., Huang, Y., Haldar, S., & Verdin, E. (2017) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsDiet and metabolism studies

Cited by 493

BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure

Duan, Q., McMahon, S., Anand, P., Shah, H., Thomas, S., Salunga, H. T., Huang, Y., Zhang, R., Sahadevan, A., Lemieux, M. E., et al. (2017) · Science Translational Medicine

Protein Degradation and InhibitorsCardiac Fibrosis and Remodeling

Cited by 262

A transcriptional switch governs fibroblast activation in heart disease

Alexanian, M., Przytycki, P. F., Micheletti, R., Padmanabhan, A., Ye, L., Travers, J. G., Gonzalez-Teran, B., Silva, A. C., Duan, Q., Ranade, S. S., et al. (2021) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 238

Chromatin remodelling drives immune cell–fibroblast communication in heart failure

Alexanian, M., Padmanabhan, A., Nishino, T., Travers, J. G., Ye, L., Pelonero, A., Lee, C. Y., Sadagopan, N., Huang, Y., Auclair, K., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 140

Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease

Theodoris, C. V., Zhou, P., Liu, L., Zhang, Y., Nishino, T., Huang, Y., Kostina, A., Ranade, S. S., Gifford, C. A., Uspenskiy, V., et al. (2021) · Science

Computational Drug Discovery MethodsGene Regulatory Network Analysis

Cited by 105

BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Padmanabhan, A., Alexanian, M., Linares-Saldana, R., González-Terán, B., Andreoletti, G., Huang, Y., Connolly, A. J., Kim, W., Hsu, A., Duan, Q., et al. (2020) · Circulation

Protein Degradation and InhibitorsCongenital heart defects research

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