Majeti, Ravindra

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Majeti, R., Chao, M. P., Alizadeh, A. A., Pang, W. W., Jaiswal, S., Gibbs, K. D., van Rooijen, N., & Weissman, I. L. (2009) · Cell

Phagocytosis and Immune RegulationAcute Myeloid Leukemia Research

Cited by 1,752

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

Corces, M. R., Buenrostro, J. D., Wu, B., Greenside, P. G., Chan, S. M., Koenig, J. L., Snyder, M. P., Pritchard, J. K., Kundaje, A., Greenleaf, W. J., et al. (2016) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,151

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Dever, D. P., Bak, R. O., Reinisch, A., Camarena, J., Washington, G., Nicolas, C. E., Pavel-Dinu, M., Saxena, N., Wilkens, A. B., Mantri, S., et al. (2016) · Nature

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 864

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., Volkmer, J., Weiskopf, K., Willingham, S. B., Raveh, T., Park, C. Y., et al. (2010) · Science Translational Medicine

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 776

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia

Jan, M., Snyder, T. M., Corces-Zimmerman, M. R., Vyas, P., Weissman, I. L., Quake, S. R., & Majeti, R. (2012) · Science Translational Medicine

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 721

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

Corces-Zimmerman, M. R., Hong, W.-J., Weissman, I. L., Medeiros, B. C., & Majeti, R. (2014) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 705

CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

Majzner, R. G., Theruvath, J. L., Nellan, A., Heitzeneder, S., Cui, Y., Mount, C. W., Rietberg, S. P., Linde, M. H., Xu, P., Rota, C., et al. (2019) · Clinical Cancer Research

CAR-T cell therapy researchImmunotherapy and Immune Responses

Cited by 681

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

Buenrostro, J. D., Corces, M. R., Lareau, C. A., Wu, B., Schep, A. N., Aryee, M. J., Majeti, R., Chang, H. Y., & Greenleaf, W. J. (2018) · Cell

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 670

Targeting Cancer Stemness in the Clinic: From Hype to Hope

Saygin, C., Matei, D., Majeti, R., Reizes, O., & Lathia, J. D. (2019) · Cell Stem Cell

Cancer Cells and MetastasisMesenchymal stem cell research

Cited by 517

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

Minhas, P. S., Liu, L., Moon, P. K., Joshi, A. U., Dove, C., Mhatre, S., Contrepois, K., Wang, Q., Lee, B. A., Coronado, M., et al. (2019) · Nature Immunology

Sirtuins and Resveratrol in MedicineTryptophan and brain disorders

Cited by 501

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

Granja, J. M., Klemm, S., McGinnis, L. M., Kathiria, A. S., Mezger, A., Corces, M. R., Parks, B., Gars, E., Liedtke, M., Zheng, G. X. Y., et al. (2019) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 498

Dysregulated gene expression networks in human acute myelogenous leukemia stem cells

Majeti, R., Becker, M. W., Tian, Q., Lee, T.-L. M., Yan, X., Liu, R., Chiang, J.-H., Hood, L., Clarke, M. F., & Weissman, I. L. (2009) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 281

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

Edris, B., Weiskopf, K., Volkmer, A. K., Volkmer, J.-P., Willingham, S. B., Contreras-Trujillo, H., Liu, J., Majeti, R., West, R. B., Fletcher, J. A., et al. (2012) · Proceedings of the National Academy of Sciences

Phagocytosis and Immune RegulationImmune cells in cancer

Cited by 258

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

Bak, R. O., Dever, D. P., Reinisch, A., Cruz Hernandez, D., Majeti, R., & Porteus, M. H. (2017) · eLife

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 122

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

Green, M. R., Vicente-Dueñas, C., Romero-Camarero, I., Long Liu, C., Dai, B., González-Herrero, I., García-Ramírez, I., Alonso-Escudero, E., Iqbal, J., Chan, W. C., et al. (2014) · Nature Communications

Lymphoma Diagnosis and TreatmentViral-associated cancers and disorders

Cited by 88