Giles, Josephine R.

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Huang, A. C., Postow, M. A., Orlowski, R. J., Mick, R., Bengsch, B., Manne, S., Xu, W., Harmon, S., Giles, J. R., Wenz, B., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 1,664

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Khan, O., Giles, J. R., McDonald, S., Manne, S., Ngiow, S. F., Patel, K. P., Werner, M. T., Huang, A. C., Alexander, K. A., Wu, J. E., et al. (2019) · Nature

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 1,646

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Mathew, D., Giles, J. R., Baxter, A. E., Oldridge, D. A., Greenplate, A. R., Wu, J. E., Alanio, C., Kuri-Cervantes, L., Pampena, M. B., D’Andrea, K., et al. (2020) · Science

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,509

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

Goel, R. R., Painter, M. M., Apostolidis, S. A., Mathew, D., Meng, W., Rosenfeld, A. M., Lundgreen, K. A., Reynaldi, A., Khoury, D. S., Pattekar, A., et al. (2021) · Science

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 873

TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell-fate decision

Chen, Z., Ji, Z., Ngiow, S. F., Manne, S., Cai, Z., Huang, A. C., Johnson, J., Staupe, R. P., Bengsch, B., Xu, C., et al. (2019) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 709

Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination

Goel, R. R., Apostolidis, S. A., Painter, M. M., Mathew, D., Pattekar, A., Kuthuru, O., Gouma, S., Hicks, P., Meng, W., Rosenfeld, A. M., et al. (2021) · Science Immunology

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 655

CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

Bange, E. M., Han, N. A., Wileyto, P., Kim, J. Y., Gouma, S., Robinson, J., Greenplate, A. R., Hwee, M. A., Porterfield, F., Owoyemi, O., et al. (2021) · Nature Medicine

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 519

Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination

Painter, M. M., Mathew, D., Goel, R. R., Apostolidis, S. A., Pattekar, A., Kuthuru, O., Baxter, A. E., Herati, R. S., Oldridge, D. A., Gouma, S., et al. (2021) · Immunity

SARS-CoV-2 and COVID-19 ResearchT-cell and B-cell Immunology

Cited by 499

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

Giles, J. R., Ngiow, S. F., Manne, S., Baxter, A. E., Khan, O., Wang, P., Staupe, R., Abdel-Hakeem, M. S., Huang, H., Mathew, D., et al. (2022) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 264

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

Goel, R. R., Painter, M. M., Lundgreen, K. A., Apostolidis, S. A., Baxter, A. E., Giles, J. R., Mathew, D., Pattekar, A., Reynaldi, A., Khoury, D. S., et al. (2022) · Cell

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 207

T follicular helper cells in human efferent lymph retain lymphoid characteristics

Vella, L. A., Buggert, M., Manne, S., Herati, R. S., Sayin, I., Kuri-Cervantes, L., Bukh Brody, I., O’Boyle, K. C., Kaprielian, H., Giles, J. R., et al. (2019) · Journal of Clinical Investigation

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 155

Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Painter, M. M., Johnston, T. S., Lundgreen, K. A., Santos, J. J. S., Qin, J. S., Goel, R. R., Apostolidis, S. A., Mathew, D., Fulmer, B., Williams, J. C., et al. (2023) · Nature Immunology

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 106