Perry, George

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., et al. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 280

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases

Espay, A. J., Vizcarra, J. A., Marsili, L., Lang, A. E., Simon, D. K., Merola, A., Josephs, K. A., Fasano, A., Morgante, F., Savica, R., et al. (2019) · Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 274

Sequestration of iron by Lewy bodies in Parkinson's disease

Castellani, R. J., Siedlak, S. L., Perry, G., & Smith, M. A. (2000) · Acta Neuropathologica

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 265

Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease

DeWitt, D. A., Perry, G., Cohen, M., Doller, C., & Silver, J. (1998) · Experimental Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 261

The Vascular Impairment of Cognition Classification Consensus Study

Skrobot, O. A., O'Brien, J., Black, S., Chen, C., DeCarli, C., Erkinjuntti, T., Ford, G. A., Kalaria, R. N., Pantoni, L., Pasquier, F., et al. (2017) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 242

Abnormal Mitochondrial Dynamics in the Pathogenesis of Alzheimer's Disease

Zhu, X., Perry, G., Smith, M. A., & Wang, X. (2012) · Journal of Alzheimer's Disease

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 242

Meta-analysis of Telomere Length in Alzheimer’s Disease

Forero, D. A., González-Giraldo, Y., López-Quintero, C., Castro-Vega, L. J., Barreto, G. E., & Perry, G. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Telomeres, Telomerase, and SenescenceDementia and Cognitive Impairment Research

Cited by 229

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

Correia, S. C., Santos, R. X., Perry, G., Zhu, X., Moreira, P. I., & Smith, M. A. (2011) · Ageing Research Reviews

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 212

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

Morgan, T. E., Xie, Z., Goldsmith, S., Yoshida, T., Lanzrein, A.-S., Stone, D., Rozovsky, I., Perry, G., Smith, M. A., & Finch, C. E. (1999) · Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 195

Tau – an inhibitor of deacetylase HDAC6 function

Perez, M., Santa‐Maria, I., De Barreda, E. G., Zhu, X., Cuadros, R., Cabrero, J. R., Sanchez‐Madrid, F., Dawson, H. N., Vitek, M. P., Perry, G., et al. (2009) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 182

Associations of semaglutide with first‐time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real‐world data in the US

Wang, W., Wang, Q., Qi, X., Gurney, M., Perry, G., Volkow, N. D., Davis, P. B., Kaelber, D. C., & Xu, R. (2024) · Alzheimer's & Dementia

Diabetes Treatment and ManagementDementia and Cognitive Impairment Research

Cited by 180

Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

Castellani, R. J., Moreira, P. I., Liu, G., Dobson, J., Perry, G., Smith, M. A., & Zhu, X. (2007) · Neurochemical Research

Alzheimer's disease research and treatmentsIron Metabolism and Disorders

Cited by 180

Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model

Wang, W., Yin, J., Ma, X., Zhao, F., Siedlak, S. L., Wang, Z., Torres, S., Fujioka, H., Xu, Y., Perry, G., et al. (2017) · Human Molecular Genetics

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 175

Alzheimer disease pathology as a host response

Castellani, R. J., Lee, H.-G., Zhu, X., Perry, G., & Smith, M. A. (2008) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 171

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

Myung, N.-H., Zhu, X., Kruman, I. I., Castellani, R. J., Petersen, R. B., Siedlak, S. L., Perry, G., Smith, M. A., & Lee, H.-G. (2008) · AGE

Alzheimer's disease research and treatmentsDNA Repair Mechanisms

Cited by 170

Abnormal localization of iron regulatory protein in Alzheimer’s disease

Smith, M. A., Wehr, K., Harris, P. L. R., Siedlak, S. L., Connor, J. R., & Perry, G. (1998) · Brain Research

Iron Metabolism and DisordersAlzheimer's disease research and treatments

Cited by 162

Nanoparticle–chelator conjugates as inhibitors of amyloid-β aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer disease

Liu, G., Men, P., Kudo, W., Perry, G., & Smith, M. A. (2009) · Neuroscience Letters

Alzheimer's disease research and treatmentsNanoparticle-Based Drug Delivery

Cited by 148

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

Nunomura, A., Hofer, T., Moreira, P. I., Castellani, R. J., Smith, M. A., & Perry, G. (2009) · Acta Neuropathologica

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 148

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

Collingwood, J. F., Chong, R. K. K., Kasama, T., Cervera-Gontard, L., Dunin-Borkowski, R. E., Perry, G., Pósfai, M., Siedlak, S. L., Simpson, E. T., Smith, M. A., et al. (2008) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsIron Metabolism and Disorders

Cited by 147

Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton

Perry, G., Kawai, M., Tabaton, M., Onorato, M., Mulvihill, P., Richey, P., Morandi, A., Connolly, J., & Gambetti, P. (1991) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 140

Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer’s disease

Raina, A. K., Templeton, D. J., deak, J. C., Perry, G., & Smith, M. A. (1999) · Redox Report

Redox biology and oxidative stressAlzheimer's disease research and treatments

Cited by 120

Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer’s disease brain: A meta-analysis in human pathological specimens

Zabel, M., Nackenoff, A., Kirsch, W. M., Harrison, F. E., Perry, G., & Schrag, M. (2018) · Free Radical Biology and Medicine

Antioxidant Activity and Oxidative StressAlzheimer's disease research and treatments

Cited by 115

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

Bryan, K. J., Zhu, X., Harris, P. L., Perry, G., Castellani, R. J., Smith, M. A., & Casadesus, G. (2008) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 114

Tau biology, tauopathy, traumatic brain injury, and diagnostic challenges

Castellani, R. J., & Perry, G. (2019) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 110