Petrou, Steven

Missense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy

Heron, S. E., Smith, K. R., Bahlo, M., Nobili, L., Kahana, E., Licchetta, L., Oliver, K. L., Mazarib, A., Afawi, Z., Korczyn, A., et al. (2012) · Nature Genetics

Epilepsy research and treatmentIon channel regulation and function

Cited by 411

SCN1A mutations and epilepsy

Mulley, J. C., Scheffer, I. E., Petrou, S., Dibbens, L. M., Berkovic, S. F., & Harkin, L. A. (2005) · Human Mutation

Epilepsy research and treatmentIon channel regulation and function

Cited by 351

Progress in Understanding and Treating SCN2A-Mediated Disorders

Sanders, S. J., Campbell, A. J., Cottrell, J. R., Moller, R. S., Wagner, F. F., Auldridge, A. L., Bernier, R. A., Catterall, W. A., Chung, W. K., Empfield, J. R., et al. (2018) · Trends in Neurosciences

Epilepsy research and treatmentIon channel regulation and function

Cited by 338

Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies

Oyrer, J., Maljevic, S., Scheffer, I. E., Berkovic, S. F., Petrou, S., & Reid, C. A. (2018) · Pharmacological Reviews

Epilepsy research and treatmentIon channel regulation and function

Cited by 315

Mutations in the GABA Transporter SLC6A1 Cause Epilepsy with Myoclonic-Atonic Seizures

Carvill, G. L., McMahon, J. M., Schneider, A., Zemel, M., Myers, C. T., Saykally, J., Nguyen, J., Robbiano, A., Zara, F., Specchio, N., et al. (2015) · The American Journal of Human Genetics

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 227

Channelopathies as a genetic cause of epilepsy

Mulley, J. C., Scheffer, I. E., Petrou, S., & Berkovic, S. F. (2003) · Current Opinion in Neurology

Epilepsy research and treatmentIon channel regulation and function

Cited by 214

Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy

Liao, Y., Deprez, L., Maljevic, S., Pitsch, J., Claes, L., Hristova, D., Jordanova, A., Ala-Mello, S., Bellan-Koch, A., Blazevic, D., et al. (2010) · Brain

Epilepsy research and treatmentIon channel regulation and function

Cited by 185

SCN2A mutation associated with neonatal epilepsy, late-onset episodic ataxia, myoclonus, and pain

Liao, Y., Anttonen, A.-K., Liukkonen, E., Gaily, E., Maljevic, S., Schubert, S., Bellan-Koch, A., Petrou, S., Ahonen, V. E., Lerche, H., et al. (2010) · Neurology

Epilepsy research and treatmentIon channel regulation and function

Cited by 170

P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region

Smart, M. L., Gu, B., Panchal, R. G., Wiley, J., Cromer, B., Williams, D. A., & Petrou, S. (2003) · Journal of Biological Chemistry

Adenosine and Purinergic SignalingIon channel regulation and function

Cited by 170

Sodium channels and the neurobiology of epilepsy

Oliva, M., Berkovic, S. F., & Petrou, S. (2012) · Epilepsia

Epilepsy research and treatmentIon channel regulation and function

Cited by 124

Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model

Li, M., Jancovski, N., Jafar-Nejad, P., Burbano, L. E., Rollo, B., Richards, K., Drew, L., Sedo, A., Heighway, J., Pachernegg, S., et al. (2021) · Journal of Clinical Investigation

Epilepsy research and treatmentIon channel regulation and function

Cited by 115

“Neonatal” NaV1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour

Gazina, E. V., Leaw, B. T. W., Richards, K. L., Wimmer, V. C., Kim, T. H., Aumann, T. D., Featherby, T. J., Churilov, L., Hammond, V. E., Reid, C. A., et al. (2015) · Human Molecular Genetics

Ion channel regulation and functionEpilepsy research and treatment

Cited by 89

A childhood epilepsy mutation reveals a role for developmentally regulated splicing of a sodium channel

Xu, R., Thomas, E. A., Jenkins, M., Gazina, E. V., Chiu, C., Heron, S. E., Mulley, J. C., Scheffer, I. E., Berkovic, S. F., & Petrou, S. (2007) · Molecular and Cellular Neuroscience

Ion channel regulation and functionEpilepsy research and treatment

Cited by 84

Antisense oligonucleotide therapy for KCNT1 encephalopathy

Burbano, L. E., Li, M., Jancovski, N., Jafar-Nejad, P., Richards, K., Sedo, A., Soriano, A., Rollo, B., Jia, L., Gazina, E. V., et al. (2022) · JCI Insight

Epilepsy research and treatmentIon channel regulation and function

Cited by 80

Differential expression of exon 5 splice variants of sodium channel α subunit mRNAs in the developing mouse brain

Gazina, E. V., Richards, K. L., Mokhtar, M. B. C., Thomas, E. A., Reid, C. A., & Petrou, S. (2010) · Neuroscience

Ion channel regulation and functionRNA Research and Splicing

Cited by 63