Lopez-Dominguez, Jose Alberto

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A. A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., et al. (2017) · Cell Metabolism

Diet and metabolism studiesGenetics, Aging, and Longevity in Model Organisms

Cited by 514

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., et al. (2020) · Nature Metabolism

Sirtuins and Resveratrol in MedicineTelomeres, Telomerase, and Senescence

Cited by 420

Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis

Wiley, C. D., Sharma, R., Davis, S. S., Lopez-Dominguez, J. A., Mitchell, K. P., Wiley, S., Alimirah, F., Kim, D. E., Payne, T., Rosko, A., et al. (2021) · Cell Metabolism

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 173

SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells

Wiley, C. D., Liu, S., Limbad, C., Zawadzka, A. M., Beck, J., Demaria, M., Artwood, R., Alimirah, F., Lopez-Dominguez, J.-A., Kuehnemann, C., et al. (2019) · Cell Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 137

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Wiley, C. D., Schaum, N., Alimirah, F., Lopez-Dominguez, J. A., Orjalo, A. V., Scott, G., Desprez, P.-Y., Benz, C., Davalos, A. R., & Campisi, J. (2018) · Scientific Reports

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 124