Natoli, Gioacchino

Macrophage activation and polarization: nomenclature and experimental guidelines

Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity

Immune cells in cancerImmune responses and vaccinations

Cited by 6,337

Trained immunity: A program of innate immune memory in health and– disease

Netea, M. G., Joosten, L. A. B., Latz, E., Mills, K. H. G., Natoli, G., Stunnenberg, H. G., O’Neill, L. A. J., & Xavier, R. J. (2016) · Science

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 2,768

Transcriptional regulation of macrophage polarization: enabling diversity with identity

Lawrence, T., & Natoli, G. (2011) · Nature Reviews Immunology

Immune cells in cancerGenomics and Chromatin Dynamics

Cited by 2,284

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

De Santa, F., Totaro, M. G., Prosperini, E., Notarbartolo, S., Testa, G., & Natoli, G. (2007) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 965

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

De Santa, F., Barozzi, I., Mietton, F., Ghisletti, S., Polletti, S., Tusi, B. K., Muller, H., Ragoussis, J., Wei, C.-L., & Natoli, G. (2010) · PLoS Biology

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 934

Latent Enhancers Activated by Stimulation in Differentiated Cells

Ostuni, R., Piccolo, V., Barozzi, I., Polletti, S., Termanini, A., Bonifacio, S., Curina, A., Prosperini, E., Ghisletti, S., & Natoli, G. (2013) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 867

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages

Ghisletti, S., Barozzi, I., Mietton, F., Polletti, S., De Santa, F., Venturini, E., Gregory, L., Lonie, L., Chew, A., Wei, C.-L., et al. (2010) · Immunity

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 666

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB

Porta, C., Rimoldi, M., Raes, G., Brys, L., Ghezzi, P., Di Liberto, D., Dieli, F., Ghisletti, S., Natoli, G., De Baetselier, P., et al. (2009) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysImmune cells in cancer

Cited by 627

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

Chen, X., Barozzi, I., Termanini, A., Prosperini, E., Recchiuti, A., Dalli, J., Mietton, F., Matteoli, G., Hiebert, S., & Natoli, G. (2012) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 397

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Cuartero, S., Weiss, F. D., Dharmalingam, G., Guo, Y., Ing-Simmons, E., Masella, S., Robles-Rebollo, I., Xiao, X., Wang, Y.-F., Barozzi, I., et al. (2018) · Nature Immunology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 210

Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers

Barozzi, I., Simonatto, M., Bonifacio, S., Yang, L., Rohs, R., Ghisletti, S., & Natoli, G. (2014) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 209

The genomic landscapes of inflammation

Natoli, G., Ghisletti, S., & Barozzi, I. (2011) · Genes & Development

Genomics and Chromatin DynamicsNF-κB Signaling Pathways

Cited by 152

Big data in IBD: a look into the future

Olivera, P., Danese, S., Jay, N., Natoli, G., & Peyrin-Biroulet, L. (2019) · Nature Reviews Gastroenterology & Hepatology

Inflammatory Bowel DiseaseBig Data Technologies and Applications

Cited by 151

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors

Hashimoto, K., Suzuki, A. M., Dos Santos, A., Desterke, C., Collino, A., Ghisletti, S., Braun, E., Bonetti, A., Fort, A., Qin, X.-Y., et al. (2015) · Genome Research

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 64

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage

Collino, A., Termanini, A., Nicoli, P., Diaferia, G., Polletti, S., Recordati, C., Castiglioni, V., Caruso, D., Mitro, N., Natoli, G., et al. (2018) · PLOS Genetics

Drug Transport and Resistance MechanismsLiver physiology and pathology

Cited by 13