Patani, Rickie

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., König, J., Hortobágyi, T., Nishimura, A. L., Župunski, V., et al. (2011) · Nature Neuroscience

RNA Research and SplicingAmyotrophic Lateral Sclerosis Research

Cited by 1,165

Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration

Patani, R., Hardingham, G. E., & Liddelow, S. A. (2023) · Nature Reviews Neurology

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 531

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

Soreq, L., Rose, J., Soreq, E., Hardy, J., Trabzuni, D., Cookson, M. R., Smith, C., Ryten, M., Patani, R., & Ule, J. (2017) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 419

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

Hall, C. E., Yao, Z., Choi, M., Tyzack, G. E., Serio, A., Luisier, R., Harley, J., Preza, E., Arber, C., Crisp, S. J., et al. (2017) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 179

The microglial component of amyotrophic lateral sclerosis

Clarke, B. E., & Patani, R. (2020) · Brain

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 164

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

Tan, C. L., Kwok, J. C. F., Patani, R., ffrench-Constant, C., Chandran, S., & Fawcett, J. W. (2011) · The Journal of Neuroscience

Nerve injury and regenerationProteoglycans and glycosaminoglycans research

Cited by 160

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

Anderson, J. M., Hampton, D. W., Patani, R., Pryce, G., Crowther, R. A., Reynolds, R., Franklin, R. J. M., Giovannoni, G., Compston, D. A. S., Baker, D., et al. (2008) · Brain

Multiple Sclerosis Research StudiesAlzheimer's disease research and treatments

Cited by 141

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

Bell, K. F., Al-Mubarak, B., Fowler, J. H., Baxter, P. S., Gupta, K., Tsujita, T., Chowdhry, S., Patani, R., Chandran, S., Horsburgh, K., et al. (2011) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressCardiac Ischemia and Reperfusion

Cited by 133

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

Tyzack, G. E., Hall, C. E., Sibley, C. R., Cymes, T., Forostyak, S., Carlino, G., Meyer, I. F., Schiavo, G., Zhang, S.-C., Gibbons, G. M., et al. (2017) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 128

Astrocytes and microglia in neurodegenerative diseases: Lessons from human in vitro models

Franklin, H., Clarke, B. E., & Patani, R. (2021) · Progress in Neurobiology

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 66

Human stem cell-derived neurons: a system to study human tau function and dysfunction

Iovino, M., Patani, R., Watts, C., Chandran, S., & Spillantini, M. G. (2010) · PLoS ONE

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 40

APP antisense oligonucleotides are effective in rescuing mitochondrial phenotypes in human iPSC‐derived trisomy 21 astrocytes

Thirumalai, S., Livesey, F. J., Patani, R., & Hung, C. (2025) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 9