Pu, William T.

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

Zhou, B., Ma, Q., Rajagopal, S., Wu, S. M., Domian, I., Rivera-Feliciano, J., Jiang, D., von Gise, A., Ikeda, S., Chien, K. R., et al. (2008) · Nature

Congenital heart defects researchPluripotent Stem Cells Research

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Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

Wang, G., McCain, M. L., Yang, L., He, A., Pasqualini, F. S., Agarwal, A., Yuan, H., Jiang, D., Zhang, D., Zangi, L., et al. (2014) · Nature Medicine

Pluripotent Stem Cells ResearchMitochondrial Function and Pathology

Cited by 837

Genetic basis for congenital heart disease: Revisited: A scientific statement from the American Heart Association

Pierpont, M. E., Brueckner, M., Chung, W. K., Garg, V., Lacro, R. V., McGuire, A. L., Mital, S., Priest, J. R., Pu, W. T., Roberts, A., et al. (2018) · Circulation

Congenital heart defects researchCongenital Heart Disease Studies

Cited by 654

Cardiomyocyte Maturation: New Phase in Development

Guo, Y., & Pu, W. T. (2020) · Circulation Research

Congenital heart defects researchPluripotent Stem Cells Research

Cited by 653

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

Zangi, L., Lui, K. O., von Gise, A., Ma, Q., Ebina, W., Ptaszek, L. M., Später, D., Xu, H., Tabebordbar, M., Gorbatov, R., et al. (2013) · Nature Biotechnology

Congenital heart defects researchMesenchymal stem cell research

Cited by 646

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

von Gise, A., Lin, Z., Schlegelmilch, K., Honor, L. B., Pan, G. M., Buck, J. N., Ma, Q., Ishiwata, T., Zhou, B., Camargo, F. D., et al. (2012) · Proceedings of the National Academy of Sciences

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 573

Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

Lin, Z., von Gise, A., Zhou, P., Gu, F., Ma, Q., Jiang, J., Yau, A. L., Buck, J. N., Gouin, K. A., van Gorp, P. R. R., et al. (2014) · Circulation Research

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 403

WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways

von Gise, A., Zhou, B., Honor, L. B., Ma, Q., Petryk, A., & Pu, W. T. (2011) · Developmental Biology

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 252

A tissue-engineered scale model of the heart ventricle

MacQueen, L. A., Sheehy, S. P., Chantre, C. O., Zimmerman, J. F., Pasqualini, F. S., Liu, X., Goss, J. A., Campbell, P. H., Gonzalez, G. M., Park, S.-J., et al. (2018) · Nature Biomedical Engineering

Tissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical Applications

Cited by 227

Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles

Choi, S., Lee, K. Y., Kim, S. L., MacQueen, L. A., Chang, H., Zimmerman, J. F., Jin, Q., Peters, M. M., Ardoña, H. A. M., Liu, X., et al. (2023) · Nature Materials

3D Printing in Biomedical ResearchHydrogels: synthesis, properties, applications

Cited by 212

Development of heart valves requires Gata4 expression in endothelial-derived cells

Rivera-Feliciano, J., Lee, K.-H., Kong, S. W., Rajagopal, S., Ma, Q., Springer, Z., Izumo, S., Tabin, C. J., & Pu, W. T. (2006) · Development

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 190

Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart

Zhou, B., von Gise, A., Ma, Q., Hu, Y. W., & Pu, W. T. (2010) · Developmental Biology

Congenital heart defects researchCardiac electrophysiology and arrhythmias

Cited by 163

Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue

Park, S.-J., Zhang, D., Qi, Y., Li, Y., Lee, K. Y., Bezzerides, V. J., Yang, P., Xia, S., Kim, S. L., Liu, X., et al. (2019) · Circulation

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 140

Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease

Kathiriya, I. S., Rao, K. S., Iacono, G., Devine, W. P., Blair, A. P., Hota, S. K., Lai, M. H., Garay, B. I., Thomas, R., Gong, H. Z., et al. (2021) · Developmental Cell

Congenital heart defects researchPluripotent Stem Cells Research

Cited by 116

Effectiveness of mHealth Interventions in Improving Medication Adherence Among People with Hypertension: a Systematic Review

Xiong, S., Berkhouse, H., Schooler, M., Pu, W., Sun, A., Gong, E., & Yan, L. L. (2018) · Current Hypertension Reports

Mobile Health and mHealth ApplicationsMedication Adherence and Compliance

Cited by 106

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor

Guo, Y., Jardin, B. D., Zhou, P., Sethi, I., Akerberg, B. N., Toepfer, C. N., Ai, Y., Li, Y., Ma, Q., Guatimosim, S., et al. (2018) · Nature Communications

Congenital heart defects researchCardiac electrophysiology and arrhythmias

Cited by 96

Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation

Lin, Z., & Pu, W. T. (2014) · Stem Cell Research

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 52

CompleteMOTIFs: DNA motif discovery platform for transcription factor binding experiments

Kuttippurathu, L., Hsing, M., Liu, Y., Schmidt, B., Maskell, D. L., Lee, K., He, A., Pu, W. T., & Kong, S. W. (2011) · Bioinformatics

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 48

Rational design of a compact CRISPR-Cas9 activator for AAV-mediated delivery

Vora, S., Cheng, J., Xiao, R., VanDusen, N. J., Quintino, L., Pu, W. T., Vandenberghe, L. H., Chavez, A., & Church, G. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 42