Lea, Susan M.

His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form

Clark, S. J., Higman, V. A., Mulloy, B., Perkins, S. J., Lea, S. M., Sim, R. B., & Day, A. J. (2006) · Journal of Biological Chemistry

Complement system in diseasesRetinal Diseases and Treatments

Cited by 185

Structural basis for complement factor H linked age-related macular degeneration

Prosser, B. E., Johnson, S., Roversi, P., Herbert, A. P., Blaum, B. S., Tyrrell, J., Jowitt, T. A., Clark, S. J., Tarelli, E., Uhrín, D., et al. (2007) · The Journal of Experimental Medicine

Complement system in diseasesRetinal Diseases and Treatments

Cited by 184

Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target

Adams, O., Deme, J. C., Parker, J. L., Fowler, P. W., Lea, S. M., & Newstead, S. (2021) · Structure

Tuberculosis Research and EpidemiologyDrug Transport and Resistance Mechanisms

Cited by 63

Structural Basis of Directional Switching by the Bacterial Flagellum

Lea, S., Johnson, S., Deme, J., Furlong, E., Chevance, F., Hughes, K., & Caesar, J. (2023) · Nature Microbiology

Bacterial Genetics and BiotechnologyAdvanced Electron Microscopy Techniques and Applications

Cited by 60

Structural characterization of protein transport by the Type 9 Secretion System

Berks, B., Lauber, F., Deme, J., Liu, X., Kjær, A., Miller, H., Alcock, F., & Lea, S. (2023) · Nature Microbiology

Bacterial Genetics and BiotechnologyAdvanced Electron Microscopy Techniques and Applications

Cited by 32

Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides

Tsiftsoglou, S. A., Arnold, J. N., Roversi, P., Crispin, M. D., Radcliffe, C., Lea, S. M., Dwek, R. A., Rudd, P. M., & Sim, R. B. (2006) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Glycosylation and Glycoproteins ResearchComplement system in diseases

Cited by 29

Three small partner proteins facilitate the type VII-dependent secretion of an antibacterial nuclease

Yang, Y., Boardman, E., Deme, J., Alcock, F., Lea, S., & Palmer, T. (2023) · mBio

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

Cited by 27

Three small partner proteins facilitate the type VII-dependent secretion export of an antibacterial nuclease

Yang, Y., Boardman, E., Deme, J., Alcock, F., Lea, S., & Palmer, T. (2023) · mBio

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

Cited by 27

Structure of the conjugation surface exclusion protein TraT

Chen, N., Bukys, A., Lundgren, C. A. K., Deme, J. C., El Sayyed, H., Kapanidis, A. N., Lea, S. M., & Berks, B. C. (2025) · Communications Biology

Bacterial Genetics and BiotechnologyAdvanced Electron Microscopy Techniques and Applications

Cited by 4

Structure of the conjugation surface exclusion protein TraT

Chen, N., Bukys, A., Lundgren, C. A. K., Deme, J. C., El Sayyed, H., Kapanidis, A. N., Lea, S. M., & Berks, B. C. (2025) · Communications Biology

Bacterial Genetics and BiotechnologyAdvanced Electron Microscopy Techniques and Applications

Cited by 4