Melillo, Bruno

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Vinogradova, E. V., Zhang, X., Remillard, D., Lazar, D. C., Suciu, R. M., Wang, Y., Bianco, G., Yamashita, Y., Crowley, V. M., Schafroth, M. A., et al. (2020) · Cell

Redox biology and oxidative stressGenomics, phytochemicals, and oxidative stress

Cited by 351

Assigning functionality to cysteines by base editing of cancer dependency genes

Li, H., Ma, T., Remsberg, J. R., Won, S. J., DeMeester, K. E., Njomen, E., Ogasawara, D., Zhao, K. T., Huang, T. P., Lu, B., et al. (2023) · Nature Chemical Biology

Click Chemistry and ApplicationsProtein Degradation and Inhibitors

Cited by 62

Modular, stereocontrolled C β –H/C α –C activation of alkyl carboxylic acids

Shang, M., Feu, K. S., Vantourout, J. C., Barton, L. M., Osswald, H. L., Kato, N., Gagaring, K., McNamara, C. W., Chen, G., Hu, L., et al. (2019) · Proceedings of the National Academy of Sciences

Catalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms

Cited by 53

Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

Jette, C. A., Barnes, C. O., Kirk, S. M., Melillo, B., Smith, A. B., & Bjorkman, P. J. (2021) · Nature Communications

HIV Research and TreatmentAdvanced Electron Microscopy Techniques and Applications

Cited by 38

Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes

Ogasawara, D., Konrad, D. B., Tan, Z. Y., Carey, K. L., Luo, J., Won, S. J., Li, H., Carter, T. R., DeMeester, K. E., Njomen, E., et al. (2024) · Cell Chemical Biology

Click Chemistry and ApplicationsChemical Synthesis and Analysis

Cited by 31

Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO

Lindsey, G. L., Hockley, T. K., Gomez, A. V., Marshall, A. C., Brothers, W. R., Finney, C. T., Gross, J., Fox, A. H., Yeo, G. W., Melillo, B., et al. (2026) · Cell Chemical Biology

RNA Research and SplicingClick Chemistry and Applications

Cited by 6

Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO

Lindsey, G. L., Hockley, T. K., Gomez, A. V., Marshall, A. C., Brothers, W. R., Finney, C. T., Gross, J., Fox, A. H., Yeo, G. W., Melillo, B., et al. (2025) · Cell chemical biology

RNA Research and SplicingClick Chemistry and Applications

Cited by 6