Yang, Jeremy J.

Unexplored therapeutic opportunities in the human genome

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DrugCentral: online drug compendium

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Pharos: collating protein information to shed light on the druggable genome

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DrugCentral 2021 supports drug discovery and repositioning

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TCRD and pharos 2021: mining the human proteome for disease biology

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Pharos 2023: an integrated resource for the understudied human proteome

Kelleher, K. J., Sheils, T. K., Mathias, S. L., Yang, J. J., Metzger, V. T., Siramshetty, V. B., Nguyen, D.-T., Jensen, L. J., Vidović, D., Schürer, S. C., et al. (2023) · Nucleic Acids Research

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Badapple: promiscuity patterns from noisy evidence

Yang, J. J., Ursu, O., Lipinski, C. A., Sklar, L. A., Oprea, T. I., & Bologa, C. G. (2016) · Journal of Cheminformatics

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DrugCentral 2023 extends human clinical data and integrates veterinary drugs

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Machine learning prediction and tau-based screening identifies potential Alzheimer’s disease genes relevant to immunity

Binder, J., Ursu, O., Bologa, C., Jiang, S., Maphis, N., Dadras, S., Chisholm, D., Weick, J., Myers, O., Kumar, P., et al. (2022) · Communications Biology

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TIN-X: target importance and novelty explorer

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schürer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G., et al. (2017) · Bioinformatics

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Formalizing drug indications on the road to therapeutic intent

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Autophagy dark genes: Can we find them with machine learning?

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