Jaiswal, Siddhartha

Age-related clonal hematopoiesis associated with adverse outcomes

Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 4,841

Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease

Jaiswal, S., Natarajan, P., Silver, A. J., Gibson, C. J., Bick, A. G., Shvartz, E., McConkey, M., Gupta, N., Gabriel, S., Ardissino, D., et al. (2017) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 2,683

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

Steensma, D. P., Bejar, R., Jaiswal, S., Lindsley, R. C., Sekeres, M. A., Hasserjian, R. P., & Ebert, B. L. (2015) · Blood

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 1,971

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Majeti, R., Chao, M. P., Alizadeh, A. A., Pang, W. W., Jaiswal, S., Gibbs, K. D., van Rooijen, N., & Weissman, I. L. (2009) · Cell

Phagocytosis and Immune RegulationAcute Myeloid Leukemia Research

Cited by 1,752

Clonal hematopoiesis in human aging and disease

Jaiswal, S., & Ebert, B. L. (2019) · Science

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 1,156

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., Volkmer, J., Weiskopf, K., Willingham, S. B., Raveh, T., Park, C. Y., et al. (2010) · Science Translational Medicine

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 776

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Bick, A. G., Weinstock, J. S., Nandakumar, S. K., Fulco, C. P., Bao, E. L., Zekavat, S. M., Szeto, M. D., Liao, X., Leventhal, M. J., Nasser, J., et al. (2020) · Nature

Acute Myeloid Leukemia ResearchGenetic Associations and Epidemiology

Cited by 733

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma

Gibson, C. J., Lindsley, R. C., Tchekmedyian, V., Mar, B. G., Shi, J., Jaiswal, S., Bosworth, A., Francisco, L., He, J., Bansal, A., et al. (2017) · Journal of Clinical Oncology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 480

Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease

Jaiswal, S., & Libby, P. (2020) · Nature Reviews Cardiology

Acute Myeloid Leukemia ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 386

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Miller, P. G., Qiao, D., Rojas-Quintero, J., Honigberg, M. C., Sperling, A. S., Gibson, C. J., Bick, A. G., Niroula, A., McConkey, M. E., Sandoval, B., et al. (2022) · Blood

Chronic Obstructive Pulmonary Disease (COPD) ResearchAcute Myeloid Leukemia Research

Cited by 235

PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

Kahn, J. D., Miller, P. G., Silver, A. J., Sellar, R. S., Bhatt, S., Gibson, C., McConkey, M., Adams, D., Mar, B., Mertins, P., et al. (2018) · Blood

Protein Tyrosine PhosphatasesAcute Myeloid Leukemia Research

Cited by 225

Clonal hematopoiesis and non-hematologic disorders

Jaiswal, S. (2020) · Blood

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 182

Clonal hematopoiesis is associated with protection from Alzheimer’s disease

Bouzid, H., Belk, J. A., Jan, M., Qi, Y., Sarnowski, C., Wirth, S., Ma, L., Chrostek, M. R., Ahmad, H., Nachun, D., et al. (2023) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 169

Dnmt3a -mutated clonal hematopoiesis promotes osteoporosis

Kim, P. G., Niroula, A., Shkolnik, V., McConkey, M., Lin, A. E., Słabicki, M., Kemp, J. P., Bick, A., Gibson, C. J., Griffin, G., et al. (2021) · Journal of Experimental Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 164

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Han, M. H., Lundgren, D. H., Jaiswal, S., Chao, M., Graham, K. L., Garris, C. S., Axtell, R. C., Ho, P. P., Lock, C. B., Woodard, J. I., et al. (2012) · Journal of Experimental Medicine

Phagocytosis and Immune RegulationMultiple Sclerosis Research Studies

Cited by 157

Clonal Hematopoiesis and Its Impact on Human Health

Ahmad, H., Jahn, N., & Jaiswal, S. (2023) · Annual Review of Medicine

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 66

Clonal Hematopoiesis: Somatic Mutations in Blood Cells and Atherosclerosis

Natarajan, P., Jaiswal, S., & Kathiresan, S. (2018) · Circulation Genomic and Precision Medicine

Acute Myeloid Leukemia ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 63

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

Matatall, K. A., Wathan, T. K., Nguyen, M., Chen, H., McDonald, A., Qi, G., Belk, J. A., Florez, M. A., Le, D. T., Olarinde, T., et al. (2025) · Cell Stem Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 23

Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women’s Health Initiative Memory Study

Jakubek, Y. A., Smith, A. P., Leng, X. I., Hall, M. E., Ezzat, D., Pershad, Y., Collins, J. M., Uddin, M. M., Fardo, D. W., Natarajan, P., et al. (2025) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAcute Myeloid Leukemia Research

Cited by 9

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

Matatall, K. A., Wathan, T. K., Nguyen, M., Chen, H., McDonald, A., Qi, G., Belk, J. A., Florez, M. A., Le, D. T., Olarinde, T., et al. (2025) · Cell Stem Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 3

Somatic mutations reveal the ontogeny of human microglia

Belk, J. A., Zhang, Y., Shi, Q., Ma, L., Kalluru, R., Enciso, A. M., Reilly, E. E., Weiss, J., Li, R., Eastman, A. E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 3