Chuang, Jeffrey H.
The Jackson Laboratory for Genomic Medicine · UConn Health
10 papers on CoChatORCID 0000-0002-3298-2358
Most cited papers
- Verified
Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration
Ishimura, R., Nagy, G., Dotu, I., Zhou, H., Yang, X.-L., Schimmel, P., Senju, S., Nishimura, Y., Chuang, J. H., & Ackerman, S. L. (2014) · Science
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 455
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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
Guillen, K. P., Fujita, M., Butterfield, A. J., Scherer, S. D., Bailey, M. H., Chu, Z., DeRose, Y. S., Zhao, L., Cortes-Sanchez, E., Yang, C.-H., et al. (2022) · Nature Cancer
Cancer Cells and MetastasisBreast Cancer Treatment Studies
Cited by 416
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Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation
Ishimura, R., Nagy, G., Dotu, I., Chuang, J. H., & Ackerman, S. L. (2016) · eLife
RNA and protein synthesis mechanismsEndoplasmic Reticulum Stress and Disease
Cited by 221
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Deep learning-based cross-classifications reveal conserved spatial behaviors within tumor histological images
Noorbakhsh, J., Farahmand, S., Foroughi pour, A., Namburi, S., Caruana, D., Rimm, D., Soltanieh-ha, M., Zarringhalam, K., & Chuang, J. H. (2020) · Nature Communications
AI in cancer detectionRadiomics and Machine Learning in Medical Imaging
Cited by 206
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
PDXNET Consortium, Woo, X. Y., EurOPDX Consortium, Giordano, J., Srivastava, A., Zhao, Z.-M., Lloyd, M. W., de Bruijn, R., Suh, Y.-S., Patidar, R., et al. (2021) · Nature Genetics
Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities
Cited by 190
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Spatial mapping of cellular senescence: emerging challenges and opportunities
Gurkar, A. U., Gerencser, A. A., Mora, A. L., Nelson, A. C., Zhang, A. R., Lagnado, A. B., Enninful, A., Benz, C., Furman, D., Beaulieu, D., et al. (2023) · Nature Aging
Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics
Cited by 141
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NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.
SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 122
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Advancing biological understanding of cellular senescence with computational multiomics
Li, S., Agudelo Garcia, P. A., Aliferis, C., Becich, M. J., Calyeca, J., Cosgrove, B. D., Elisseeff, J., Farzad, N., Fertig, E. J., Glass, C., et al. (2025) · Nature Genetics
Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics
Cited by 40
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Fostering bioinformatics education through skill development of professors: Big Genomic Data Skills Training for Professors
Zhan, Y. A., Wray, C. G., Namburi, S., Glantz, S. T., Laubenbacher, R., & Chuang, J. H. (2019) · PLOS Computational Biology
Genetics, Bioinformatics, and Biomedical ResearchTeaching and Learning Programming
Cited by 18
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p21-senescent cells drive pancreatic islet dysfunction through targetable paracrine signaling in type 2 diabetes
Iwasaki, K., Carapeto, P., Abarca, C., Hela, F., Sanjines, S., Pena, S., Le, S., Pan, H., Jackson, M., Cahill, C., et al. (2026) · JCI Insight
Pancreatic function and diabetesTelomeres, Telomerase, and Senescence
Cited by 4
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