Blüthgen, Nils

Spatial partitioning of the regulatory landscape of the X-inactivation centre

Nora, E. P., Lajoie, B. R., Schulz, E. G., Giorgetti, L., Okamoto, I., Servant, N., Piolot, T., van Berkum, N. L., Meisig, J., Sedat, J., et al. (2012) · Nature

Genomics and Chromatin DynamicsGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 2,895

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

Herrgård, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Blüthgen, N., Borger, S., Costenoble, R., Heinemann, M., et al. (2008) · Nature Biotechnology

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 588

MicroRNA control of protein expression noise

Schmiedel, J. M., Klemm, S. L., Zheng, Y., Sahay, A., Blüthgen, N., Marks, D. S., & van Oudenaarden, A. (2015) · Science

MicroRNA in disease regulationGene Regulatory Network Analysis

Cited by 395

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L. J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., et al. (2022) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 218

scPerturb: harmonized single-cell perturbation data

Peidli, S., Green, T. D., Shen, C., Gross, T., Min, J., Garda, S., Yuan, B., Schumacher, L. J., Taylor-King, J. P., Marks, D. S., et al. (2024) · Nature Methods

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 194

Recurrent design patterns in the feedback regulation of the mammalian signalling network

Legewie, S., Herzel, H., Westerhoff, H. V., & Blüthgen, N. (2008) · Molecular Systems Biology

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 112

Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma

Schoetz, U., Klein, D., Hess, J., Shnayien, S., Spoerl, S., Orth, M., Mutlu, S., Hennel, R., Sieber, A., Ganswindt, U., et al. (2021) · Cell Death & Disease

Telomeres, Telomerase, and SenescenceHead and Neck Cancer Studies

Cited by 74

Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting

Steinbrecht, D., Minia, I., Milek, M., Meisig, J., Blüthgen, N., & Landthaler, M. (2024) · Molecular Systems Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 14

Identifiability and experimental design in perturbation studies

Gross, T., & Blüthgen, N. (2020) · Bioinformatics

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 11

Robust network inference using response logic

Gross, T., Wongchenko, M. J., Yan, Y., & Blüthgen, N. (2019) · Bioinformatics

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 7