Batlle, Eduard

Cancer stem cells revisited

Batlle, E., & Clevers, H. (2017) · Nature Medicine

Cancer Cells and MetastasisMesenchymal stem cell research

Cited by 2,769

Transforming Growth Factor-β Signaling in Immunity and Cancer

Batlle, E., & Massagué, J. (2019) · Immunity

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 2,366

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A.-P., et al. (2002) · Cell

Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer

Cited by 2,030

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Tauriello, D. V. F., Palomo-Ponce, S., Stork, D., Berenguer-Llergo, A., Badia-Ramentol, J., Iglesias, M., Sevillano, M., Ibiza, S., Cañellas, A., Hernando-Momblona, X., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 1,851

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Calon, A., Lonardo, E., Berenguer-Llergo, A., Espinet, E., Hernando-Momblona, X., Iglesias, M., Sevillano, M., Palomo-Ponce, S., Tauriello, D. V. F., Byrom, D., et al. (2015) · Nature Genetics

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 1,070

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

Calon, A., Espinet, E., Palomo-Ponce, S., Tauriello, D. V. F., Iglesias, M., Céspedes, M. V., Sevillano, M., Nadal, C., Jung, P., Zhang, X. H.-F., et al. (2012) · Cancer Cell

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 1,060

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

Merlos-Suárez, A., Barriga, F. M., Jung, P., Iglesias, M., Céspedes, M. V., Rossell, D., Sevillano, M., Hernando-Momblona, X., da Silva-Diz, V., Muñoz, P., et al. (2011) · Cell Stem Cell

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 934

Isolation and in vitro expansion of human colonic stem cells

Jung, P., Sato, T., Merlos-Suárez, A., Barriga, F. M., Iglesias, M., Rossell, D., Auer, H., Gallardo, M., Blasco, M. A., Sancho, E., et al. (2011) · Nature Medicine

Cancer Cells and MetastasisHematopoietic Stem Cell Transplantation

Cited by 709

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects

Mereu, E., Lafzi, A., Moutinho, C., Ziegenhain, C., McCarthy, D. J., Álvarez-Varela, A., Batlle, E., Sagar, Grün, D., Lau, J. K., et al. (2020) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 499

Overcoming TGFβ-mediated immune evasion in cancer

Tauriello, D. V. F., Sancho, E., & Batlle, E. (2022) · Nature Reviews Cancer

TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers

Cited by 377

TGF-beta in CAF-mediated tumor growth and metastasis

Calon, A., Tauriello, D. V. F., & Batlle, E. (2014) · Seminars in Cancer Biology

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 342

The circadian molecular clock creates epidermal stem cell heterogeneity

Janich, P., Pascual, G., Merlos-Suárez, A., Batlle, E., Ripperger, J., Albrecht, U., Cheng, H.-Y. M., Obrietan, K., Di Croce, L., & Benitah, S. A. (2011) · Nature

Hair Growth and DisordersCircadian rhythm and melatonin

Cited by 326

Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells

Cañellas-Socias, A., Cortina, C., Hernando-Momblona, X., Palomo-Ponce, S., Mulholland, E. J., Turon, G., Mateo, L., Conti, S., Roman, O., Sevillano, M., et al. (2022) · Nature

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 256

Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Pérez-González, C., Ceada, G., Greco, F., Matejčić, M., Gómez-González, M., Castro, N., Menendez, A., Kale, S., Krndija, D., Clark, A. G., et al. (2021) · Nature Cell Biology

Cellular Mechanics and Interactions3D Printing in Biomedical Research

Cited by 225

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities

Russo, M., Chen, M., Mariella, E., Peng, H., Rehman, S. K., Sancho, E., Sogari, A., Toh, T. S., Balaban, N. Q., Batlle, E., et al. (2024) · Nature Reviews Cancer

Cancer Cells and MetastasisMathematical Biology Tumor Growth

Cited by 210

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

Herpers, B., Eppink, B., James, M. I., Cortina, C., Cañellas-Socias, A., Boj, S. F., Hernando-Momblona, X., Glodzik, D., Roovers, R. C., van de Wetering, M., et al. (2022) · Nature Cancer

Monoclonal and Polyclonal Antibodies ResearchCancer Cells and Metastasis

Cited by 178

Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy

Linares, J., Sallent-Aragay, A., Badia-Ramentol, J., Recort-Bascuas, A., Méndez, A., Manero-Rupérez, N., Re, D. L., Rivas, E. I., Guiu, M., Zwick, M., et al. (2023) · Nature Communications

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 109