Shiva, Sruti

Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement

Nolfi-Donegan, D., Braganza, A., & Shiva, S. (2020) · Redox Biology

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 1,488

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Phinney, D. G., Di Giuseppe, M., Njah, J., Sala, E., Shiva, S., St Croix, C. M., Stolz, D. B., Watkins, S. C., Di, Y. P., Leikauf, G. D., et al. (2015) · Nature Communications

Extracellular vesicles in diseaseMesenchymal stem cell research

Cited by 1,007

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

Bueno, M., Lai, Y.-C., Romero, Y., Brands, J., St. Croix, C. M., Kamga, C., Corey, C., Herazo-Maya, J. D., Sembrat, J., Lee, J. S., et al. (2015) · Journal of Clinical Investigation

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMitochondrial Function and Pathology

Cited by 627

Nitrate and nitrite in biology, nutrition and therapeutics

Lundberg, J. O., Gladwin, M. T., Ahluwalia, A., Benjamin, N., Bryan, N. S., Butler, A., Cabrales, P., Fago, A., Feelisch, M., Ford, P. C., et al. (2009) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 617

The emerging biology of the nitrite anion

Gladwin, M. T., Schechter, A. N., Kim-Shapiro, D. B., Patel, R. P., Hogg, N., Shiva, S., Cannon, R. O., Kelm, M., Wink, D. A., Espey, M. G., et al. (2005) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 609

Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

Shiva, S., Huang, Z., Grubina, R., Sun, J., Ringwood, L. A., MacArthur, P. H., Xu, X., Murphy, E., Darley-Usmar, V. M., & Gladwin, M. T. (2007) · Circulation Research

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 599

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Shiva, S., Sack, M. N., Greer, J. J., Duranski, M., Ringwood, L. A., Burwell, L., Wang, X., MacArthur, P. H., Shoja, A., Raghavachari, N., et al. (2007) · The Journal of Experimental Medicine

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 555

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 541

Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology

van Faassen, E. E., Bahrami, S., Feelisch, M., Hogg, N., Kelm, M., Kim‐Shapiro, D. B., Kozlov, A. V., Li, H., Lundberg, J. O., Mason, R., et al. (2009) · Medicinal Research Reviews

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 435

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

Hendgen-Cotta, U. B., Merx, M. W., Shiva, S., Schmitz, J., Becher, S., Klare, J. P., Steinhoff, H.-J., Goedecke, A., Schrader, J., Gladwin, M. T., et al. (2008) · Proceedings of the National Academy of Sciences

Hemoglobin structure and functionCardiac Ischemia and Reperfusion

Cited by 418

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

Villagra, J., Shiva, S., Hunter, L. A., Machado, R. F., Gladwin, M. T., & Kato, G. J. (2007) · Blood

Hemoglobinopathies and Related DisordersPlatelet Disorders and Treatments

Cited by 384

Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis

Shiva, S., Wang, X., Ringwood, L. A., Xu, X., Yuditskaya, S., Annavajjhala, V., Miyajima, H., Hogg, N., Harris, Z. L., & Gladwin, M. T. (2006) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 359

IPF lung fibroblasts have a senescent phenotype

Álvarez, D., Cárdenes, N., Sellarés, J., Bueno, M., Corey, C., Hanumanthu, V. S., Peng, Y., D’Cunha, H., Sembrat, J., Nouraie, M., et al. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 342

Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation

Gladwin, M. T., Raat, N. J. H., Shiva, S., Dezfulian, C., Hogg, N., Kim-Shapiro, D. B., & Patel, R. P. (2006) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 329

Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

Brookes, P. S., Levonen, A.-L., Shiva, S., Sarti, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 298

Human neuroglobin functions as a redox-regulated nitrite reductase

Tiso, M., Tejero, J., Basu, S., Azarov, I., Wang, X., Simplaceanu, V., Frizzell, S., Jayaraman, T., Geary, L., Shapiro, C., et al. (2011) · Journal of Biological Chemistry

Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide

Cited by 287

Nitrite reductase activity of cytochrome c

Basu, S., Azarova, N. A., Font, M. D., King, S. B., Hogg, N., Gladwin, M. T., Shiva, S., & Kim-Shapiro, D. B. (2008) · Journal of Biological Chemistry

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 214

Nitrite: A physiological store of nitric oxide and modulator of mitochondrial function

Shiva, S. (2013) · Redox Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 207

Nitrite regulates hypoxic vasodilation via myoglobin-dependent nitric oxide generation

Totzeck, M., Hendgen-Cotta, U. B., Luedike, P., Berenbrink, M., Klare, J. P., Steinhoff, H.-J., Semmler, D., Shiva, S., Williams, D., Kipar, A., et al. (2012) · Circulation

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 202

Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics

DEZFULIAN, C., RAAT, N., SHIVA, S., & GLADWIN, M. (2007) · Cardiovascular Research

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 198

Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation

Zuckerbraun, B. S., Shiva, S., Ifedigbo, E., Mathier, M. A., Mollen, K. P., Rao, J., Bauer, P. M., Choi, J. J. W., Curtis, E., Choi, A. M. K., et al. (2010) · Circulation

Pulmonary Hypertension Research and TreatmentsNitric Oxide and Endothelin Effects

Cited by 192

Nitrite Anion Provides Potent Cytoprotective and Antiapoptotic Effects as Adjunctive Therapy to Reperfusion for Acute Myocardial Infarction

Gonzalez, F. M., Shiva, S., Vincent, P. S., Ringwood, L. A., Hsu, L.-Y., Hon, Y. Y., Aletras, A. H., Cannon, R. O., Gladwin, M. T., & Arai, A. E. (2008) · Circulation

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 175

Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhibition of mitochondrial complex I

Dezfulian, C., Shiva, S., Alekseyenko, A., Pendyal, A., Beiser, D. G., Munasinghe, J. P., Anderson, S. A., Chesley, C. F., Vanden Hoek, T. L., & Gladwin, M. T. (2009) · Circulation

Cardiac Arrest and ResuscitationCardiac Ischemia and Reperfusion

Cited by 174

Biological activity of nitric oxide in the plasmatic compartment

Wang, X., Tanus-Santos, J. E., Reiter, C. D., Dejam, A., Shiva, S., Smith, R. D., Hogg, N., & Gladwin, M. T. (2004) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 164