Cleary, Brian

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Schiebinger, G., Shu, J., Tabaka, M., Cleary, B., Subramanian, V., Solomon, A., Gould, J., Liu, S., Lin, S., Berube, P., et al. (2019) · Cell

Single-cell and spatial transcriptomicsPluripotent Stem Cells Research

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Systematic mapping of functional enhancer–promoter connections with CRISPR interference

Fulco, C. P., Munschauer, M., Anyoha, R., Munson, G., Grossman, S. R., Perez, E. M., Kane, M., Cleary, B., Lander, E. S., & Engreitz, J. M. (2016) · Science

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 643

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Frangieh, C. J., Melms, J. C., Thakore, P. I., Geiger-Schuller, K. R., Ho, P., Luoma, A. M., Cleary, B., Jerby-Arnon, L., Malu, S., Cuoco, M. S., et al. (2021) · Nature Genetics

Cancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomics

Cited by 276

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Schiebinger, G., Shu, J., Tabaka, M., Cleary, B., Subramanian, V., Solomon, A., Gould, J., Liu, S., Lin, S., Berube, P., et al. (2019) · Cell

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 139

Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuits

Binan, L., Danquah, S., Valakh, V., Simonton, B., Bezney, J., Nehme, R., Cleary, B., & Farhi, S. L. (2023) · Cell

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 139

Efficient Generation of Transcriptomic Profiles by Random Composite Measurements

Cleary, B., Cong, L., Cheung, A., Lander, E. S., & Regev, A. (2017) · Cell

Gene expression and cancer classificationSparse and Compressive Sensing Techniques

Cited by 114

Scalable genetic screening for regulatory circuits using compressed Perturb-seq

Yao, D., Binan, L., Bezney, J., Simonton, B., Freedman, J., Frangieh, C. J., Dey, K., Geiger-Schuller, K., Eraslan, B., Gusev, A., et al. (2024) · Nature Biotechnology

CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics

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