Perdew, Gary H.

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

Beischlag, T. V., Morales, J. L., Hollingshead, B. D., & Perdew, G. H. (2008) · Critical Reviews™ in Eukaryotic Gene Expression

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 727

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

Hubbard, T. D., Murray, I. A., Bisson, W. H., Lahoti, T. S., Gowda, K., Amin, S. G., Patterson, A. D., & Perdew, G. H. (2015) · Scientific Reports

Gut microbiota and healthToxic Organic Pollutants Impact

Cited by 377

A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins

Carlson, D. B., & Perdew, G. H. (2002) · Journal of Biochemical and Molecular Toxicology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 184

Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic Mice

Flaveny, C. A., Murray, I. A., Chiaro, C. R., & Perdew, G. H. (2009) · Molecular Pharmacology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 124

Ligand Activation of Peroxisome Proliferator–Activated Receptor β/δ (PPARβ/δ) Attenuates Carbon Tetrachloride Hepatotoxicity by Downregulating Proinflammatory Gene Expression

Shan, W., Palkar, P. S., Murray, I. A., McDevitt, E. I., Kennett, M. J., Kang, B. H., Isom, H. C., Perdew, G. H., Gonzalez, F. J., & Peters, J. M. (2008) · Toxicological Sciences

Peroxisome Proliferator-Activated ReceptorsDrug-Induced Hepatotoxicity and Protection

Cited by 97

Mapping the 90 kDa heat shock protein binding region of the Ah receptor

Perdew, G. H., & Bradfield, C. A. (1996) · IUBMB Life

Heat shock proteins researchToxic Organic Pollutants Impact

Cited by 63

Suppression of Cytokine-Mediated Complement Factor Gene Expression through Selective Activation of the Ah Receptor with 3′,4′-Dimethoxy-α-naphthoflavone

Murray, I. A., Flaveny, C. A., Chiaro, C. R., Sharma, A. K., Tanos, R. S., Schroeder, J. C., Amin, S. G., Bisson, W. H., Kolluri, S. K., & Perdew, G. H. (2011) · Molecular Pharmacology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 53

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

Perkins, A., Phillips, J., Kerkvliet, N., Tanguay, R., Perdew, G., Kolluri, S., & Bisson, W. (2014) · Biology

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 52

Selective programming of CCR10(+) innate lymphoid cells in skin-draining lymph nodes for cutaneous homeostatic regulation

Yang, J., Hu, S., Zhao, L., Kaplan, D. H., Perdew, G. H., & Xiong, N. (2016) · Nature Immunology

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 49

Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity

Murray, I. A., Reen, R. K., Leathery, N., Ramadoss, P., Bonati, L., Gonzalez, F. J., Peters, J. M., & Perdew, G. H. (2005) · Archives of Biochemistry and Biophysics

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 41