Sasaki, Yo

Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration

Araki, T., Sasaki, Y., & Milbrandt, J. (2004) · Science

Sirtuins and Resveratrol in MedicineNerve injury and regeneration

Cited by 1,060

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Mills, K. F., Yoshida, S., Stein, L. R., Grozio, A., Kubota, S., Sasaki, Y., Redpath, P., Migaud, M. E., Apte, R. S., Uchida, K., et al. (2016) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 930

The SARM1 toll/interleukin-1 receptor domain possesses intrinsic NAD(+) cleavage activity that promotes pathological axonal degeneration

Essuman, K., Summers, D. W., Sasaki, Y., Mao, X., DiAntonio, A., & Milbrandt, J. (2017) · Neuron

Nerve injury and regenerationCell death mechanisms and regulation

Cited by 619

SARM1 activation triggers axon degeneration locally via NAD + destruction

Gerdts, J., Brace, E. J., Sasaki, Y., DiAntonio, A., & Milbrandt, J. (2015) · Science

Nerve injury and regenerationCell death mechanisms and regulation

Cited by 593

Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors

Honda, S., Sasaki, Y., Ohsawa, K., Imai, Y., Nakamura, Y., Inoue, K., & Kohsaka, S. (2001) · The Journal of Neuroscience

Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 561

Iba1 Is an Actin-Cross-Linking Protein in Macrophages/Microglia

Sasaki, Y., Ohsawa, K., Kanazawa, H., Kohsaka, S., & Imai, Y. (2001) · Biochemical and Biophysical Research Communications

Cellular Mechanics and InteractionsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 373

Stimulation of Nicotinamide Adenine Dinucleotide Biosynthetic Pathways Delays Axonal Degeneration after Axotomy

Sasaki, Y., Araki, T., & Milbrandt, J. (2006) · The Journal of Neuroscience

Nerve injury and regenerationSirtuins and Resveratrol in Medicine

Cited by 269

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion

Sasaki, Y., Nakagawa, T., Mao, X., DiAntonio, A., & Milbrandt, J. (2016) · eLife

Nerve injury and regenerationSirtuins and Resveratrol in Medicine

Cited by 192

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

Sasaki, Y., Vohra, B. P. S., Baloh, R. H., & Milbrandt, J. (2009) · The Journal of Neuroscience

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 152

Clinical significance of the second cycle response to cisplatin-based chemotherapy as preoperative treatment for esophageal squamous cell carcinoma

Akita, H., Doki, Y., Miyata, H., Hirao, T., Yano, M., Takachi, K., Miyashiro, I., Sasaki, Y., Ishikawa, O., Ohigashi, H., et al. (2006) · Journal of Surgical Oncology

Esophageal Cancer Research and TreatmentGastric Cancer Management and Outcomes

Cited by 28

Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility

Franczyk, M. P., Qi, N., Stromsdorfer, K. L., Li, C., Yamaguchi, S., Itoh, H., Yoshino, M., Sasaki, Y., Brookheart, R. T., Finck, B. N., et al. (2021) · Endocrinology

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 23

Disruption of lactate metabolism in the peripheral nervous system leads to motor-selective deficits

Bloom, A. J., Hackett, A. R., Strickland, A., Yamada, Y., Ippolito, J., Schmidt, R. E., Sasaki, Y., DiAntonio, A., & Milbrandt, J. (2022) · Glia

Hereditary Neurological DisordersPeripheral Neuropathies and Disorders

Cited by 8