Lefkowitz, Robert J.

Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.

Koch, W. J., Hawes, B. E., Inglese, J., Luttrell, L. M., & Lefkowitz, R. J. (1994) · Journal of Biological Chemistry

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 421

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1

Hara, M. R., Kovacs, J. J., Whalen, E. J., Rajagopal, S., Strachan, R. T., Grant, W., Towers, A. J., Williams, B., Lam, C. M., Xiao, K., et al. (2011) · Nature

Cancer-related Molecular PathwaysReceptor Mechanisms and Signaling

Cited by 420

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

Shukla, A. K., Xiao, K., & Lefkowitz, R. J. (2011) · Trends in Biochemical Sciences

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 418

Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Chen, W., ten Berge, D., Brown, J., Ahn, S., Hu, L. A., Miller, W. E., Caron, M. G., Barak, L. S., Nusse, R., & Lefkowitz, R. J. (2003) · Science

Wnt/β-catenin signaling in development and cancerReceptor Mechanisms and Signaling

Cited by 334

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

Staus, D. P., Strachan, R. T., Manglik, A., Pani, B., Kahsai, A. W., Kim, T. H., Wingler, L. M., Ahn, S., Chatterjee, A., Masoudi, A., et al. (2016) · Nature

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 330

New Roles for β-Arrestins in Cell Signaling: Not Just for Seven-Transmembrane Receptors

Lefkowitz, R. J., Rajagopal, K., & Whalen, E. J. (2006) · Molecular Cell

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 301

Catecholamines, Cardiac β-Adrenergic Receptors, and Heart Failure

Lefkowitz, R. J., Rockman, H. A., & Koch, W. J. (2000) · Circulation

Receptor Mechanisms and SignalingHeart Failure Treatment and Management

Cited by 291

The impact of aging on adrenergic receptor function: clinical and biochemical aspects

Heinsimer, J. A., & Lefkowitz, R. J. (1985) · Journal of the American Geriatrics Society

Receptor Mechanisms and SignalingPhosphodiesterase function and regulation

Cited by 67