Lotz, Martin K.

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

Miyaki, S., Sato, T., Inoue, A., Otsuki, S., Ito, Y., Yokoyama, S., Kato, Y., Takemoto, F., Nakasa, T., Yamashita, S., et al. (2010) · Genes & Development

Osteoarthritis Treatment and MechanismsMicroRNA in disease regulation

Cited by 660

Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis

Caramés, B., Taniguchi, N., Otsuki, S., Blanco, F. J., & Lotz, M. (2010) · Arthritis & Rheumatism

Osteoarthritis Treatment and MechanismsAutophagy in Disease and Therapy

Cited by 632

Value of biomarkers in osteoarthritis: current status and perspectives

Lotz, M., Martel-Pelletier, J., Christiansen, C., Brandi, M.-L., Bruyère, O., Chapurlat, R., Collette, J., Cooper, C., Giacovelli, G., Kanis, J. A., et al. (2013) · Annals of the Rheumatic Diseases

Osteoarthritis Treatment and MechanismsProteoglycans and glycosaminoglycans research

Cited by 328

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

Lotz, M. K., & Caramés, B. (2011) · Nature Reviews Rheumatology

Osteoarthritis Treatment and MechanismsAutophagy in Disease and Therapy

Cited by 314

FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis

Matsuzaki, T., Alvarez-Garcia, O., Mokuda, S., Nagira, K., Olmer, M., Gamini, R., Miyata, K., Akasaki, Y., Su, A. I., Asahara, H., et al. (2018) · Science Translational Medicine

Osteoarthritis Treatment and MechanismsFOXO transcription factor regulation

Cited by 271

The relationship of autophagy defects to cartilage damage during joint aging in a mouse model

Caramés, B., Olmer, M., Kiosses, W. B., & Lotz, M. K. (2015) · Arthritis & Rheumatology

Osteoarthritis Treatment and MechanismsAutophagy in Disease and Therapy

Cited by 204

Chemotaxis of human articular chondrocytes and mesenchymal stem cells

Mishima, Y., & Lotz, M. (2008) · Journal of Orthopaedic Research

Osteoarthritis Treatment and MechanismsMesenchymal stem cell research

Cited by 192

Boning up on autophagy: The role of autophagy in skeletal biology

Shapiro, I. M., Layfield, R., Lotz, M., Settembre, C., & Whitehouse, C. (2014) · Autophagy

Autophagy in Disease and TherapyBone Metabolism and Diseases

Cited by 175

Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy

Nogueira-Recalde, U., Lorenzo-Gómez, I., Blanco, F. J., Loza, M. I., Grassi, D., Shirinsky, V., Shirinsky, I., Lotz, M., Robbins, P. D., Domínguez, E., et al. (2019) · EBioMedicine

Osteoarthritis Treatment and MechanismsTelomeres, Telomerase, and Senescence

Cited by 155