Vainchenker, William

Mutation in TET2 in Myeloid Cancers

Delhommeau, F., Dupont, S., Valle, V. D., James, C., Trannoy, S., Massé, A., Kosmider, O., Le Couedic, J.-P., Robert, F., Alberdi, A., et al. (2009) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchMyeloproliferative Neoplasms: Diagnosis and Treatment

Cited by 1,776

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

Quivoron, C., Couronné, L., Della Valle, V., Lopez, C. K., Plo, I., Wagner-Ballon, O., Do Cruzeiro, M., Delhommeau, F., Arnulf, B., Stern, M.-H., et al. (2011) · Cancer Cell

Acute Myeloid Leukemia ResearchChromatin Remodeling and Cancer

Cited by 924

JAK/STAT signaling in hematological malignancies

Vainchenker, W., & Constantinescu, S. N. (2013) · Oncogene

Cytokine Signaling Pathways and InteractionsMyeloproliferative Neoplasms: Diagnosis and Treatment

Cited by 528

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

Ho, Y.-H., del Toro, R., Rivera-Torres, J., Rak, J., Korn, C., García-García, A., Macías, D., González-Gómez, C., del Monte, A., Wittner, M., et al. (2019) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 315

Prominent role of TGF-β1 in thrombopoietin-induced myelofibrosis in mice

Chagraoui, H., Komura, E., Tulliez, M., Giraudier, S., Vainchenker, W., & Wendling, F. (2002) · Blood

Myeloproliferative Neoplasms: Diagnosis and TreatmentTGF-β signaling in diseases

Cited by 238

Spi-1/PU.1 Transgenic Mice Develop Multistep Erythroleukemias

Moreau-Gachelin, F., Wendling, F., Molina, T., Denis, N., Titeux, M., Grimber, G., Briand, P., Vainchenker, W., & Tavitian, A. (1996) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchT-cell and Retrovirus Studies

Cited by 189

FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia

Raslova, H., Komura, E., Le Couédic, J. P., Larbret, F., Debili, N., Feunteun, J., Danos, O., Albagli, O., Vainchenker, W., & Favier, R. (2004) · Journal of Clinical Investigation

Platelet Disorders and TreatmentsAcute Myeloid Leukemia Research

Cited by 174

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

Rodriguez-Meira, A., Norfo, R., Wen, S., Chédeville, A. L., Rahman, H., O’Sullivan, J., Wang, G., Louka, E., Kretzschmar, W. W., Paterson, A., et al. (2023) · Nature Genetics

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 158

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Gilles, L., Bluteau, D., Boukour, S., Chang, Y., Zhang, Y., Robert, T., Dessen, P., Debili, N., Bernard, O. A., Vainchenker, W., et al. (2009) · Blood

Platelet Disorders and TreatmentsAcute Myeloid Leukemia Research

Cited by 80

Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases

Josefsson, E. C., Vainchenker, W., & James, C. (2020) · International Journal of Molecular Sciences

Platelet Disorders and TreatmentsCell death mechanisms and regulation

Cited by 68

Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms

Mosca, M., Hermange, G., Tisserand, A., Noble, R., Marzac, C., Marty, C., Le Sueur, C., Campario, H., Vertenoeil, G., El-Khoury, M., et al. (2021) · Blood

Myeloproliferative Neoplasms: Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 57

P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis

Mahfoudhi, E., Lordier, L., Marty, C., Pan, J., Roy, A., Roy, L., Rameau, P., Abbes, S., Debili, N., Raslova, H., et al. (2016) · Oncotarget

Platelet Disorders and TreatmentsCancer-related Molecular Pathways

Cited by 53

Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice

Kosmider, O., Denis, N., Lacout, C., Vainchenker, W., Dubreuil, P., & Moreau-Gachelin, F. (2005) · Cancer Cell

Acute Myeloid Leukemia ResearchT-cell and Retrovirus Studies

Cited by 49