Specht, Charles A.

A Chitin Synthase and Its Regulator Protein Are Critical for Chitosan Production and Growth of the Fungal Pathogen Cryptococcus neoformans

Banks, I. R., Specht, C. A., Donlin, M. J., Gerik, K. J., Levitz, S. M., & Lodge, J. K. (2005) · Eukaryotic Cell

Fungal and yeast genetics researchFungal Infections and Studies

Cited by 245

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

Wiesner, D. L., Specht, C. A., Lee, C. K., Smith, K. D., Mukaremera, L., Lee, S. T., Lee, C. G., Elias, J. A., Nielsen, J. N., Boulware, D. R., et al. (2015) · PLOS Pathogens

Fungal Infections and StudiesStudies on Chitinases and Chitosanases

Cited by 214

Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

Loures, F. V., Röhm, M., Lee, C. K., Santos, E., Wang, J. P., Specht, C. A., Calich, V. L. G., Urban, C. F., & Levitz, S. M. (2015) · PLOS Pathogens

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmune Response and Inflammation

Cited by 165

Distinct Patterns of Dendritic Cell Cytokine Release Stimulated by Fungal β-Glucans and Toll-Like Receptor Agonists

Huang, H., Ostroff, G. R., Lee, C. K., Wang, J. P., Specht, C. A., & Levitz, S. M. (2009) · Infection and Immunity

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 146

Vaccines for human fungal diseases: close but still a long way to go

Oliveira, L. V. N., Wang, R., Specht, C. A., & Levitz, S. M. (2021) · npj Vaccines

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 135

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

Ramirez-Ortiz, Z. G., Lee, C. K., Wang, J. P., Boon, L., Specht, C. A., & Levitz, S. M. (2011) · Cell Host & Microbe

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 121

KRE genes are required for β‐1,6‐glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans

Gilbert, N. M., Donlin, M. J., Gerik, K. J., Specht, C. A., Djordjevic, J. T., Wilson, C. F., Sorrell, T. C., & Lodge, J. K. (2010) · Molecular Microbiology

Fungal Infections and StudiesFungal and yeast genetics research

Cited by 113

Molecular cloning and characterization of chitinase genes from Candida albicans.

McCreath, K. J., Specht, C. A., & Robbins, P. W. (1995) · Proceedings of the National Academy of Sciences

Studies on Chitinases and ChitosanasesFungal and yeast genetics research

Cited by 101

Candida albicans CHT3 encodes the functional homolog of the Cts1 chitinase of Saccharomyces cerevisiae

Dünkler, A., Walther, A., Specht, C. A., & Wendland, J. (2005) · Fungal Genetics and Biology

Fungal and yeast genetics researchStudies on Chitinases and Chitosanases

Cited by 98

Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species

Specht, C. A., Lee, C. K., Huang, H., Hester, M. M., Liu, J., Luckie, B. A., Torres Santana, M. A., Mirza, Z., Khoshkenar, P., Abraham, A., et al. (2017) · mBio

Fungal Infections and StudiesBacterial Infections and Vaccines

Cited by 91

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma

Guerra, E. S., Lee, C. K., Specht, C. A., Yadav, B., Huang, H., Akalin, A., Huh, J. R., Mueller, C., & Levitz, S. M. (2017) · PLOS Pathogens

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 88