Dear, James W.

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Abani, O., Abbas, A., Abbas, F., Abbas, M., Abbasi, S., Abbass, H., Abbott, A., Abdallah, N., Abdelaziz, A., Abdelfattah, M., et al. (2021) · The Lancet

COVID-19 Clinical Research StudiesRespiratory Support and Mechanisms

Cited by 1,983

Long‐term adverse effects of paracetamol – a review

McCrae, J. C., Morrison, E. E., MacIntyre, I. M., Dear, J. W., & Webb, D. J. (2018) · British Journal of Clinical Pharmacology

Inflammatory mediators and NSAID effectsPharmaceutical Practices and Patient Outcomes

Cited by 308

Small interfering RNA: Discovery, pharmacology and clinical development—An introductory review

Ranasinghe, P., Addison, M. L., Dear, J. W., & Webb, D. J. (2023) · British Journal of Pharmacology

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 138

Effect of the UK's revised paracetamol poisoning management guidelines on admissions, adverse reactions and costs of treatment

Bateman, D. N., Carroll, R., Pettie, J., Yamamoto, T., Elamin, M. E. M. O., Peart, L., Dow, M., Coyle, J., Cranfield, K. R., Hook, C., et al. (2014) · British Journal of Clinical Pharmacology

Poisoning and overdose treatmentsDrug-Induced Hepatotoxicity and Protection

Cited by 131

Regular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial

MacIntyre, I. M., Turtle, E. J., Farrah, T. E., Graham, C., Dear, J. W., Webb, D. J., McCallum, M., Melville, V., Fok, H., McCrae, J. C., et al. (2022) · Circulation

Blood Pressure and Hypertension StudiesInflammatory mediators and NSAID effects

Cited by 80

Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use

Bateman, D. N., & Dear, J. W. (2019) · Toxicology Research

Poisoning and overdose treatmentsDrug-Induced Hepatotoxicity and Protection

Cited by 53

Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial)

Morrison, E. E., Oatey, K., Gallagher, B., Grahamslaw, J., O'Brien, R., Black, P., Oosthuyzen, W., Lee, R. J., Weir, C. J., Henriksen, D., et al. (2019) · eBioMedicine

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 48

A systematic review of the effect of paracetamol on blood pressure in hypertensive and non‐hypertensive subjects

Turtle, E. J., Dear, J. W., & Webb, D. J. (2013) · British Journal of Clinical Pharmacology

Blood Pressure and Hypertension StudiesInflammatory mediators and NSAID effects

Cited by 48

Stratification of paracetamol overdose patients using new toxicity biomarkers: current candidates and future challenges

Dear, J. W., & Antoine, D. J. (2014) · Expert Review of Clinical Pharmacology

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 34

Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973–2023 with particular focus on contributions published from Edinburgh and Denver

Bateman, D. N., Dart, R. C., Dear, J. W., Prescott, L. F., & Rumack, B. H. (2023) · Clinical Toxicology

Poisoning and overdose treatmentsDrug-Induced Hepatotoxicity and Protection

Cited by 25

Impact of reducing the threshold for acetylcysteine treatment in acute paracetamol poisoning: The recent United Kingdom experience

Bateman, D. N., Dear, J. W., Carroll, R., Pettie, J., Yamamoto, T., Elamin, M. E. M. O., Peart, L., Dow, M., Coyle, J., Gray, A., et al. (2014) · Clinical Toxicology

Poisoning and overdose treatmentsDrug-Induced Hepatotoxicity and Protection

Cited by 20

Cryopreserved human alternatively activated macrophages promote resolution of acetaminophen-induced liver injury in mouse

Candela, M. E., Addison, M., Aird, R., Man, T.-Y., Cartwright, J. A., Ashmore-Harris, C., Kilpatrick, A. M., Starkey Lewis, P. J., Drape, A., Barnett, M., et al. (2025) · npj Regenerative Medicine

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 11

Fomepizole should not be used more liberally in paracetamol overdose

Dear, J. W. (2023) · British Journal of Clinical Pharmacology

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 11

Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series

Bateman, D. N., Dear, J. W., Eddleston, M., & Vale, J. A. (2022) · Clinical Toxicology

Poisoning and overdose treatmentsDrug-Induced Hepatotoxicity and Protection

Cited by 1