Gao, Wei

Why 90% of clinical drug development fails and how to improve it?

Sun, D., Gao, W., Hu, H., & Zhou, S. (2022) · Acta Pharmaceutica Sinica B

Computational Drug Discovery MethodsAnimal testing and alternatives

Cited by 1,763

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ding, K., Lu, Y., Nikolovska-Coleska, Z., Wang, G., Qiu, S., Shangary, S., Gao, W., Qin, D., Stuckey, J., Krajewski, K., et al. (2006) · Journal of Medicinal Chemistry

Cancer-related Molecular PathwaysComputational Drug Discovery Methods

Cited by 702

Structure-based design of potent non-peptide MDM2 inhibitors

Ding, K., Lu, Y., Nikolovska-Coleska, Z., Qiu, S., Ding, Y., Gao, W., Stuckey, J., Krajewski, K., Roller, P. P., Tomita, Y., et al. (2005) · Journal of the American Chemical Society

Cancer-related Molecular PathwaysComputational Drug Discovery Methods

Cited by 657

Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer

Gao, W., Ye, G., Duan, X., Yang, X., & Yang, V. C. (2017) · International Journal of Nanomedicine

Nanoparticle-Based Drug DeliveryDrug Transport and Resistance Mechanisms

Cited by 57

A folate modified pH sensitive targeted polymeric micelle alleviated systemic toxicity of doxorubicin (DOX) in multi-drug resistant tumor bearing mice

Li, X., Yang, X., Lin, Z., Wang, D., Mei, D., He, B., Wang, X., Wang, X., Zhang, Q., & Gao, W. (2015) · European Journal of Pharmaceutical Sciences

Nanoparticle-Based Drug DeliveryDrug Transport and Resistance Mechanisms

Cited by 56