Fussenegger, Martin

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types

Kelm, J. M., Timmins, N. E., Brown, C. J., Fussenegger, M., & Nielsen, L. K. (2003) · Biotechnology and Bioengineering

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 934

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

Kojima, R., Bojar, D., Rizzi, G., Hamri, G. C.-E., El-Baba, M. D., Saxena, P., Ausländer, S., Tan, K. R., & Fussenegger, M. (2018) · Nature Communications

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 748

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

Guetg, C., Lienemann, P., Sirri, V., Grummt, I., Hernandez‐Verdun, D., Hottiger, M. O., Fussenegger, M., & Santoro, R. (2010) · The EMBO Journal

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 184

Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells

Tigges, M., & Fussenegger, M. (2006) · Metabolic Engineering

Viral Infectious Diseases and Gene Expression in InsectsEndoplasmic Reticulum Stress and Disease

Cited by 178

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant.

Folcher, M., Oesterle, S., Zwicky, K., Thekkottil, T., Heymoz, J., Hohmann, M., Christen, M., Daoud El-Baba, M., Buchmann, P., & Fussenegger, M. (2014) · Nature Communications

Photoreceptor and optogenetics researchGene Regulatory Network Analysis

Cited by 130

Ectopic expression of human mTOR increases viability, robustness, cell size, proliferation, and antibody production of chinese hamster ovary cells

Dreesen, I. A. J., & Fussenegger, M. (2011) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 110

Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl‐2/bcl‐xL on productivity, cell survival, and mitochondria number in CHO‐DG44 grown in suspension and serum‐free media

Meents, H., Enenkel, B., Eppenberger, H. M., Werner, R. G., & Fussenegger, M. (2002) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 92

Bottom-up de novo design of functional proteins with complex structural features

Yang, C., Sesterhenn, F., Bonet, J., van Aalen, E. A., Scheller, L., Abriata, L. A., Cramer, J. T., Wen, X., Rosset, S., Georgeon, S., et al. (2021) · Nature Chemical Biology

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 84

Differential effect of exocytic SNAREs on the production of recombinant proteins in mammalian cells

Peng, R., Abellan, E., & Fussenegger, M. (2011) · Biotechnology and Bioengineering

Cellular transport and secretionViral Infectious Diseases and Gene Expression in Insects

Cited by 61