Skaar, Eric P.

Menaquinone biosynthesis potentiates haem toxicity in Staphylococcus aureus

Wakeman, C. A., Hammer, N. D., Stauff, D. L., Attia, A. S., Anzaldi, L. L., Dikalov, S. I., Calcutt, M. W., & Skaar, E. P. (2012) · Molecular Microbiology

Bacterial Genetics and BiotechnologyAntimicrobial Resistance in Staphylococcus

Cited by 94

IsdB-dependent hemoglobin binding is required for acquisition of heme by Staphylococcus aureus

Pishchany, G., Sheldon, J. R., Dickson, C. F., Alam, M. T., Read, T. D., Gell, D. A., Heinrichs, D. E., & Skaar, E. P. (2014) · The Journal of Infectious Diseases

Antimicrobial Resistance in StaphylococcusHemoglobin structure and function

Cited by 88

The Host Protein Calprotectin Modulates the Helicobacter pylori cag Type IV Secretion System via Zinc Sequestration

Gaddy, J. A., Radin, J. N., Loh, J. T., Piazuelo, M. B., Kehl-Fie, T. E., Delgado, A. G., Ilca, F. T., Peek, R. M., Cover, T. L., Chazin, W. J., et al. (2014) · PLoS Pathogens

Helicobacter pylori-related gastroenterology studiesS100 Proteins and Annexins

Cited by 87

Staphylococcus aureus haem oxygenases are differentially regulated by iron and haem

Reniere, M. L., & Skaar, E. P. (2008) · Molecular Microbiology

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

Cited by 86

Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host

Perry, W. J., Spraggins, J. M., Sheldon, J. R., Grunenwald, C. M., Heinrichs, D. E., Cassat, J. E., Skaar, E. P., & Caprioli, R. M. (2019) · Proceedings of the National Academy of Sciences

Antimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensing

Cited by 84

The impact of metal availability on immune function during infection

Monteith, A. J., & Skaar, E. P. (2021) · Trends in Endocrinology & Metabolism

Trace Elements in HealthIron Metabolism and Disorders

Cited by 83

Staphylococcus aureus HrtA Is an ATPase Required for Protection against Heme Toxicity and Prevention of a Transcriptional Heme Stress Response

Stauff, D. L., Bagaley, D., Torres, V. J., Joyce, R., Anderson, K. L., Kuechenmeister, L., Dunman, P. M., & Skaar, E. P. (2008) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyAntimicrobial Resistance in Staphylococcus

Cited by 83

Bacillus anthracis HssRS signalling to HrtAB regulates haem resistance during infection

Stauff, D. L., & Skaar, E. P. (2009) · Molecular Microbiology

Bacillus and Francisella bacterial researchBacterial Genetics and Biotechnology

Cited by 81

Nfu facilitates the maturation of iron‐sulfur proteins and participates in virulence in S taphylococcus aureus

Mashruwala, A. A., Pang, Y. Y., Rosario‐Cruz, Z., Chahal, H. K., Benson, M. A., Mike, L. A., Skaar, E. P., Torres, V. J., Nauseef, W. M., & Boyd, J. M. (2015) · Molecular Microbiology

Metalloenzymes and iron-sulfur proteinsBacterial Genetics and Biotechnology

Cited by 79

Subcellular Localization of the Staphylococcus aureus Heme Iron Transport Components IsdA and IsdB

Pishchany, G., Dickey, S. E., & Skaar, E. P. (2009) · Infection and Immunity

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

Cited by 77

An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration

Lonergan, Z. R., Nairn, B. L., Wang, J., Hsu, Y.-P., Hesse, L. E., Beavers, W. N., Chazin, W. J., Trinidad, J. C., VanNieuwenhze, M. S., Giedroc, D. P., et al. (2019) · Cell Reports

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 76

Multi-metal restriction by calprotectin impacts de novo flavin biosynthesis in Acinetobacter baumannii

Wang, J., Lonergan, Z. R., Gonzalez-Gutierrez, G., Nairn, B. L., Maxwell, C. N., Zhang, Y., Andreini, C., Karty, J. A., Chazin, W. J., Trinidad, J. C., et al. (2019) · Cell chemical biology

Bacterial Genetics and BiotechnologyBiochemical and Molecular Research

Cited by 76

Acinetobacter baumannii OxyR Regulates the Transcriptional Response to Hydrogen Peroxide

Juttukonda, L. J., Green, E. R., Lonergan, Z. R., Heffern, M. C., Chang, C. J., & Skaar, E. P. (2019) · Infection and Immunity

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 75

S100 Proteins in the Innate Immune Response to Pathogens

Kozlyuk, N., Monteith, A. J., Garcia, V., Damo, S. M., Skaar, E. P., & Chazin, W. J. (2019) · Methods in Molecular Biology

S100 Proteins and AnnexinsAntimicrobial Peptides and Activities

Cited by 72

Inter- and intraspecies metabolite exchange promotes virulence of antibiotic-resistant Staphylococcus aureus

Hammer, N. D., Cassat, J. E., Noto, M. J., Lojek, L. J., Chadha, A. D., Schmitz, J. E., Creech, C. B., & Skaar, E. P. (2014) · Cell Host & Microbe

Antimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensing

Cited by 72

Transferrin iron starvation therapy for lethal bacterial and fungal infections

Lin, L., Pantapalangkoor, P., Tan, B., Bruhn, K. W., Ho, T., Nielsen, T., Skaar, E. P., Zhang, Y., Bai, R., Wang, A., et al. (2014) · Journal of Infectious Diseases

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 68

Dietary Manganese Promotes Staphylococcal Infection of the Heart

Juttukonda, L. J., Berends, E. T. M., Zackular, J. P., Moore, J. L., Stier, M. T., Zhang, Y., Schmitz, J. E., Beavers, W. N., Wijers, C. D., Gilston, B. A., et al. (2017) · Cell Host & Microbe

Infective Endocarditis Diagnosis and ManagementHeavy Metal Exposure and Toxicity

Cited by 68

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence

Haley, K. P., Delgado, A. G., Piazuelo, M. B., Mortensen, B. L., Correa, P., Damo, S. M., Chazin, W. J., Skaar, E. P., & Gaddy, J. A. (2015) · Infection and Immunity

Helicobacter pylori-related gastroenterology studiesS100 Proteins and Annexins

Cited by 68

The chlorite dismutase (HemQ) from Staphylococcus aureus has a redox-sensitive heme and is associated with the small colony variant phenotype

Mayfield, J. A., Hammer, N. D., Kurker, R. C., Chen, T. K., Ojha, S., Skaar, E. P., & DuBois, J. L. (2013) · Journal of Biological Chemistry

Metal-Catalyzed Oxygenation MechanismsPorphyrin Metabolism and Disorders

Cited by 63

Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System

Knippel, R. J., Wexler, A. G., Miller, J. M., Beavers, W. N., Weiss, A., de Crécy-Lagard, V., Edmonds, K. A., Giedroc, D. P., & Skaar, E. P. (2020) · Cell Host & Microbe

Clostridium difficile and Clostridium perfringens researchBacterial Genetics and Biotechnology

Cited by 62

The Acinetobacter baumannii Znu System Overcomes Host-Imposed Nutrient Zinc Limitation

Hesse, L. E., Lonergan, Z. R., Beavers, W. N., & Skaar, E. P. (2019) · Infection and Immunity

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 59

Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation

Gaddy, J. A., Radin, J. N., Cullen, T. W., Chazin, W. J., Skaar, E. P., Trent, M. S., & Algood, H. M. S. (2015) · mBio

Helicobacter pylori-related gastroenterology studiesBacterial biofilms and quorum sensing

Cited by 59

Regulation of host hemoglobin binding by the Staphylococcus aureus Clp proteolytic system

Farrand, A. J., Reniere, M. L., Ingmer, H., Frees, D., & Skaar, E. P. (2013) · Journal of Bacteriology

Heat shock proteins researchAntimicrobial Resistance in Staphylococcus

Cited by 56

Clostridioides difficile ferrosome organelles combat nutritional immunity

Pi, H., Sun, R., McBride, J. R., Kruse, A. R. S., Gibson-Corley, K. N., Krystofiak, E. S., Nicholson, M. R., Spraggins, J. M., Zhou, Q., & Skaar, E. P. (2023) · Nature

Clostridium difficile and Clostridium perfringens researchBacterial Genetics and Biotechnology

Cited by 54