Dorrestein, Pieter C.

A Synthesis-Based Reverse Metabolomics Approach for the Discovery of Chemical Structures from Humans and Animals.

Dorrestein, P., Gentry, E., Collins, S., Panitchpakdi, M., Belda-Ferre, P., Stewart, A., Wang, M., Jarmusch, A., Avila-Pacheco, J., Plichta, D., et al. (2021) · Nature

Metabolomics and Mass Spectrometry StudiesGut microbiota and health

Cited by 197

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Foley, M. H., Walker, M. E., Stewart, A. K., O’Flaherty, S., Gentry, E. C., Patel, S., Beaty, V. V., Allen, G., Pan, M., Simpson, J. B., et al. (2023) · Nature Microbiology

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 181

The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases

Fogelson, K. A., Dorrestein, P. C., Zarrinpar, A., & Knight, R. (2023) · Gastroenterology

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 177

Deconvolution and Database Search of Complex Tandem Mass Spectra of Intact Proteins

Liu, X., Inbar, Y., Dorrestein, P. C., Wynne, C., Edwards, N., Souda, P., Whitelegge, J. P., Bafna, V., & Pevzner, P. A. (2010) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 170

ReDU: a framework to find and reanalyze public mass spectrometry data

Jarmusch, A. K., Wang, M., Aceves, C. M., Advani, R. S., Aguirre, S., Aksenov, A. A., Aleti, G., Aron, A. T., Bauermeister, A., Bolleddu, S., et al. (2020) · Nature Methods

Metabolomics and Mass Spectrometry StudiesResearch Data Management Practices

Cited by 152

How bile acids and the microbiota interact to shape host immunity

Lee, M. H., Nuccio, S.-P., Mohanty, I., Hagey, L. R., Dorrestein, P. C., Chu, H., & Raffatellu, M. (2024) · Nature Reviews Immunology

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 143

Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease

Aleti, G., Baker, J. L., Tang, X., Alvarez, R., Dinis, M., Tran, N. C., Melnik, A. V., Zhong, C., Ernst, M., Dorrestein, P. C., et al. (2019) · mBio

Oral microbiology and periodontitis researchMicrobial Natural Products and Biosynthesis

Cited by 107

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

Behnsen, J., Zhi, H., Aron, A. T., Subramanian, V., Santus, W., Lee, M. H., Gerner, R. R., Petras, D., Liu, J. Z., Green, K. D., et al. (2021) · Nature Communications

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 101

Coupling Targeted and Untargeted Mass Spectrometry for Metabolome-Microbiome-Wide Association Studies of Human Fecal Samples

Melnik, A. V., da Silva, R. R., Hyde, E. R., Aksenov, A. A., Vargas, F., Bouslimani, A., Protsyuk, I., Jarmusch, A. K., Tripathi, A., Alexandrov, T., et al. (2017) · Analytical Chemistry

Metabolomics and Mass Spectrometry StudiesGut microbiota and health

Cited by 87

Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism

Edlund, A., Yang, Y., Yooseph, S., Hall, A. P., Nguyen, D. D., Dorrestein, P. C., Nelson, K. E., He, X., Lux, R., Shi, W., et al. (2015) · The ISME Journal

Oral microbiology and periodontitis researchGut microbiota and health

Cited by 84

Native mass spectrometry-based metabolomics identifies metal-binding compounds

Aron, A. T., Petras, D., Schmid, R., Gauglitz, J. M., Büttel, I., Antelo, L., Zhi, H., Nuccio, S.-P., Saak, C. C., Malarney, K. P., et al. (2022) · Nature Chemistry

Mass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry Studies

Cited by 79

Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide

Xue, J., Zhou, D., Poulsen, O., Imamura, T., Hsiao, Y.-H., Smith, T. H., Malhotra, A., Dorrestein, P., Knight, R., & Haddad, G. G. (2017) · American Journal of Respiratory Cell and Molecular Biology

Obstructive Sleep Apnea ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 77

Multi-omics Analysis of Periodontal Pocket Microbial Communities Pre- and Posttreatment

Califf, K. J., Schwarzberg-Lipson, K., Garg, N., Gibbons, S. M., Caporaso, J. G., Slots, J., Cohen, C., Dorrestein, P. C., & Kelley, S. T. (2017) · mSystems

Oral microbiology and periodontitis researchBacterial biofilms and quorum sensing

Cited by 66

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors

Reher, R., Aron, A. T., Fajtová, P., Stincone, P., Wagner, B., Pérez-Lorente, A. I., Liu, C., Shalom, I. Y. B., Bittremieux, W., Wang, M., et al. (2022) · Nature Communications

Microbial Natural Products and BiosynthesisMetabolomics and Mass Spectrometry Studies

Cited by 53

Total Synthesis and Biological Assessment of Novel Albicidins Discovered by Mass Spectrometric Networking

von Eckardstein, L., Petras, D., Dang, T., Cociancich, S., Sabri, S., Grätz, S., Kerwat, D., Seidel, M., Pesic, A., Dorrestein, P. C., et al. (2017) · Chemistry – A European Journal

Microbial Natural Products and BiosynthesisAdvanced Synthetic Organic Chemistry

Cited by 36

NPOmix: a machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

Leão, T. F., Wang, M., da Silva, R., Gurevich, A., Bauermeister, A., Gomes, P. W. P., Brejnrod, A., Glukhov, E., Aron, A. T., Louwen, J. J. R., et al. (2021) · PNAS Nexus

Microbial Natural Products and BiosynthesisMetabolomics and Mass Spectrometry Studies

Cited by 32

Functional genomics and metabolomics advance the ethnobotany of the Samoan traditional medicine “matalafi”

Molimau-Samasoni, S., Woolner, V. H., Foliga, S. T., Robichon, K., Patel, V., Andreassend, S. K., Sheridan, J. P., Te Kawa, T., Gresham, D., Miller, D., et al. (2021) · Proceedings of the National Academy of Sciences

Ethnobotanical and Medicinal Plants StudiesPhytochemistry and Biological Activities

Cited by 20

MS2Prop: A machine learning model that directly generates de novo predictions of drug-likeness of natural products from unannotated MS/MS spectra

Voronov, G., Lightheart, R., Frandsen, A., Bargh, B., Haynes, S. E., Spencer, E., Schoenhardt, K. E., Davidson, C., Schaum, A., Macherla, V. R., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Computational Drug Discovery MethodsMass Spectrometry Techniques and Applications

Cited by 18

Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data

Jo, T., Kim, J., Bice, P., Huynh, K., Wang, T., Arnold, M., Meikle, P. J., Giles, C., Kaddurah-Daouk, R., Saykin, A. J., et al. (2023) · eBioMedicine

Dementia and Cognitive Impairment ResearchMetabolomics and Mass Spectrometry Studies

Cited by 15