Margolskee, Alison

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Margolskee, A., Darwich, A. S., Pepin, X., Aarons, L., Galetin, A., Rostami-Hodjegan, A., Carlert, S., Hammarberg, M., Hilgendorf, C., Johansson, P., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 69

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Darwich, A. S., Margolskee, A., Pepin, X., Aarons, L., Galetin, A., Rostami-Hodjegan, A., Carlert, S., Hammarberg, M., Hilgendorf, C., Johansson, P., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsComputational Drug Discovery Methods

Cited by 45

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Margolskee, A., Darwich, A. S., Pepin, X., Pathak, S. M., Bolger, M. B., Aarons, L., Rostami-Hodjegan, A., Angstenberger, J., Graf, F., Laplanche, L., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 43

Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models

Hansmann, S., Darwich, A., Margolskee, A., Aarons, L., & Dressman, J. (2016) · Journal of Pharmacy and Pharmacology

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 38

Dynamics and bifurcation of a model for hormonal control of the menstrual cycle with inhibin delay

Margolskee, A., & Selgrade, J. F. (2011) · Mathematical Biosciences

Hypothalamic control of reproductive hormonesMathematical and Theoretical Epidemiology and Ecology Models

Cited by 18

Translational Population‐Pharmacodynamic Modeling of a Novel Long‐Acting siRNA Therapy, Inclisiran, for the Treatment of Hypercholesterolemia

Gosselin, N. H., Schuck, V. J. A., Barriere, O., Kulmatycki, K., Margolskee, A., Smith, P., & He, Y. (2023) · Clinical Pharmacology & Therapeutics

Lipoproteins and Cardiovascular HealthRNA Interference and Gene Delivery

Cited by 17