Grabrucker, Andreas M.

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

Schmeisser, M. J., Ey, E., Wegener, S., Bockmann, J., Stempel, A. V., Kuebler, A., Janssen, A.-L., Udvardi, P. T., Shiban, E., Spilker, C., et al. (2012) · Nature

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 638

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

Grabrucker, A. M., Schmeisser, M. J., Schoen, M., & Boeckers, T. M. (2011) · Trends in Cell Biology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 233

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

Grabrucker, A. M., Knight, M. J., Proepper, C., Bockmann, J., Joubert, M., Rowan, M., Nienhaus, G. U., Garner, C. C., Bowie, J. U., Kreutz, M. R., et al. (2011) · The EMBO Journal

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 228

Nanoparticle transport across the blood brain barrier

Grabrucker, A. M., Ruozi, B., Belletti, D., Pederzoli, F., Forni, F., Vandelli, M. A., & Tosi, G. (2016) · Tissue Barriers

Barrier Structure and Function StudiesNanoparticle-Based Drug Delivery

Cited by 217

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability

Küry, S., van Woerden, G. M., Besnard, T., Proietti Onori, M., Latypova, X., Towne, M. C., Cho, M. T., Prescott, T. E., Ploeg, M. A., Sanders, S., et al. (2017) · The American Journal of Human Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 185

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders

Grabrucker, S., Jannetti, L., Eckert, M., Gaub, S., Chhabra, R., Pfaender, S., Mangus, K., Reddy, P. P., Rankovic, V., Schmeisser, M. J., et al. (2014) · Brain

Genetics and Neurodevelopmental DisordersTrace Elements in Health

Cited by 175

Characterization of biometal profiles in neurological disorders

Pfaender, S., & Grabrucker, A. M. (2014) · Metallomics

Trace Elements in HealthHeavy Metal Exposure and Toxicity

Cited by 117

Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport

Tosi, G., Vilella, A., Chhabra, R., Schmeisser, M. J., Boeckers, T. M., Ruozi, B., Vandelli, M. A., Forni, F., Zoli, M., & Grabrucker, A. M. (2014) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryBarrier Structure and Function Studies

Cited by 56

Nanoparticles as Blood–Brain Barrier Permeable CNS Targeted Drug Delivery Systems

Grabrucker, A. M., Chhabra, R., Belletti, D., Forni, F., Vandelli, M. A., Ruozi, B., & Tosi, G. (2013) · Topics in Medicinal Chemistry

Nanoparticle-Based Drug DeliveryBarrier Structure and Function Studies

Cited by 53

Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies

Sarowar, T., & Grabrucker, A. M. (2016) · Neural Plasticity

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 46

Targeting Metal Homeostasis as a Therapeutic Strategy for Alzheimer’s Disease

Department of Biomedical, M. A. N. S., Vilella, A., Daini, E., Department of Biomedical, M. A. N. S., De Benedictis, C. A., Cellular Neurobiology and Neuro-Nanotechnology Lab, D. O. B. S., Grabrucker, A. M., Cellular Neurobiology and Neuro-Nanotechnology Lab, D. O. B. S., Bernal Institute, U. O. L., & Health Research Institute (HRI), U. O. L. (2020) · Alzheimer’s Disease: Drug Discovery

Alzheimer's disease research and treatmentsTrace Elements in Health

Cited by 12

Unveiling the crucial neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Küry, S., Stanton, J. E., van Woerden, G., Hsieh, T.-C., Rosenfelt, C., Scott-Boyer, M. P., Most, V., Wang, T., Papendorf, J. J., de Konink, C., et al. (2024) · medRxiv

Genetics and Neurodevelopmental DisordersUbiquitin and proteasome pathways

Cited by 6

Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Küry, S., Stanton, J. E., van Woerden, G. M., Bosc-Rosati, A., Hsieh, T.-C., Bray, L., Oloudé, M., Rosenfelt, C., Scott-Boyer, M. P., Most, V., et al. (2025) · Nature Communications

Ubiquitin and proteasome pathwaysGenetics and Neurodevelopmental Disorders

Cited by 3