Edwards, Peter A.

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

Chawla, A., Boisvert, W. A., Lee, C.-H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., et al. (2001) · Molecular Cell

Cholesterol and Lipid MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 1,347

Pleiotropic Roles of Bile Acids in Metabolism

de Aguiar Vallim, T. Q., Tarling, E. J., & Edwards, P. A. (2013) · Cell Metabolism

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 1,209

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

Bennett, B. J., Vallim, T. Q. D. A., Wang, Z., Shih, D. M., Meng, Y., Gregory, J., Allayee, H., Lee, R., Graham, M., Crooke, R., et al. (2013) · Cell Metabolism

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 1,070

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

Venkateswaran, A., Laffitte, B. A., Joseph, S. B., Mak, P. A., Wilpitz, D. C., Edwards, P. A., & Tontonoz, P. (2000) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 1,005

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

Kast, H. R., Goodwin, B., Tarr, P. T., Jones, S. A., Anisfeld, A. M., Stoltz, C. M., Tontonoz, P., Kliewer, S., Willson, T. M., & Edwards, P. A. (2002) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 916

LXR signaling couples sterol metabolism to proliferation in the acquired immune response

Bensinger, S. J., Bradley, M. N., Joseph, S. B., Zelcer, N., Janssen, E. M., Hausner, M. A., Shih, R., Parks, J. S., Edwards, P. A., Jamieson, B. D., et al. (2008) · Cell

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 711

FXR, a multipurpose nuclear receptor

Lee, F. Y., Lee, H., Hubbert, M. L., Edwards, P. A., & Zhang, Y. (2006) · Trends in Biochemical Sciences

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 344

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

Sene, A., Khan, A. A., Cox, D., Nakamura, R. E. I., Santeford, A., Kim, B. M., Sidhu, R., Onken, M. D., Harbour, J. W., Hagbi-Levi, S., et al. (2013) · Cell Metabolism

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 277

Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia

Zhang, Y., Yin, L., Anderson, J., Ma, H., Gonzalez, F. J., Willson, T. M., & Edwards, P. A. (2010) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 112