Khatri, Purvesh

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Arunachalam, P. S., Wimmers, F., Mok, C. K. P., Perera, R. A. P. M., Scott, M., Hagan, T., Sigal, N., Feng, Y., Bristow, L., Tak-Yin Tsang, O., et al. (2020) · Science

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,186

A novel signaling pathway impact analysis

Tarca, A. L., Draghici, S., Khatri, P., Hassan, S. S., Mittal, P., Kim, J.-S., Kim, C. J., Kusanovic, J. P., & Romero, R. (2009) · Bioinformatics

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 1,031

Reliability and reproducibility issues in DNA microarray measurements

DRAGHICI, S., KHATRI, P., EKLUND, A., & SZALLASI, Z. (2006) · Trends in Genetics

Gene expression and cancer classificationMolecular Biology Techniques and Applications

Cited by 590

A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring

Alpert, A., Pickman, Y., Leipold, M., Rosenberg-Hasson, Y., Ji, X., Gaujoux, R., Rabani, H., Starosvetsky, E., Kveler, K., Schaffert, S., et al. (2019) · Nature Medicine

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 513

Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine

Li, C., Lee, A., Grigoryan, L., Arunachalam, P. S., Scott, M. K. D., Trisal, M., Wimmers, F., Sanyal, M., Weidenbacher, P. A., Feng, Y., et al. (2022) · Nature Immunology

SARS-CoV-2 and COVID-19 ResearchImmunotherapy and Immune Responses

Cited by 505

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

Pluvinage, J. V., Haney, M. S., Smith, B. A. H., Sun, J., Iram, T., Bonanno, L., Li, L., Lee, D. P., Morgens, D. W., Yang, A. C., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 459

Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

Sweeney, T. E., Wong, H. R., & Khatri, P. (2016) · Science Translational Medicine

Sepsis Diagnosis and TreatmentGene expression and cancer classification

Cited by 334

Single-cell chromatin modification profiling reveals increased epigenetic variations with aging

Cheung, P., Vallania, F., Warsinske, H. C., Donato, M., Schaffert, S., Chang, S. E., Dvorak, M., Dekker, C. L., Davis, M. M., Utz, P. J., et al. (2018) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 323

Gene annotation bias impedes biomedical research

Haynes, W. A., Tomczak, A., & Khatri, P. (2018) · Scientific Reports

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 192

Gene annotation bias impedes biomedical research

Haynes, W. A., Tomczak, A., & Khatri, P. (2017) · Scientific Reports

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 192

Cellular senescence impairs the reversibility of pulmonary arterial hypertension

van der Feen, D. E., Bossers, G. P. L., Hagdorn, Q. A. J., Moonen, J.-R., Kurakula, K., Szulcek, R., Chappell, J., Vallania, F., Donato, M., Kok, K., et al. (2020) · Science Translational Medicine

Pulmonary Hypertension Research and TreatmentsTelomeres, Telomerase, and Senescence

Cited by 150

Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity

Napier, B. A., Brubaker, S. W., Sweeney, T. E., Monette, P., Rothmeier, G. H., Gertsvolf, N. A., Puschnik, A., Carette, J. E., Khatri, P., & Monack, D. M. (2016) · Journal of Experimental Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 149