Gingras, Anne-Claude

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

Gill, M. K., Christova, T., Zhang, Y. Y., Gregorieff, A., Zhang, L., Narimatsu, M., Song, S., Xiong, S., Couzens, A. L., Tong, J., et al. (2018) · Nature Communications

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 95

Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1

Meiri, D., Marshall, C. B., Mokady, D., LaRose, J., Mullin, M., Gingras, A.-C., Ikura, M., & Rottapel, R. (2014) · Nature Communications

Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling

Cited by 70

Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

Liu, J., Budylowski, P., Samson, R., Griffin, B. D., Babuadze, G., Rathod, B., Colwill, K., Abioye, J. A., Schwartz, J. A., Law, R., et al. (2022) · Science Advances

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

Cited by 56

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen

O’Meara, T. R., O’Meara, M. J., Polvi, E. J., Pourhaghighi, M. R., Liston, S. D., Lin, Z.-Y., Veri, A. O., Emili, A., Gingras, A.-C., & Cowen, L. E. (2019) · PLoS Biology

Heat shock proteins researchFungal and yeast genetics research

Cited by 49

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

O’Connor, C. M., Leonard, D., Wiredja, D., Avelar, R. A., Wang, Z., Schlatzer, D., Bryson, B., Tokala, E., Taylor, S. E., Upadhyay, A., et al. (2020) · Oncogene

Protein Tyrosine PhosphatasesMelanoma and MAPK Pathways

Cited by 48

Beyond hairballs: The use of quantitative mass spectrometry data to understand protein–protein interactions

Gingras, A.-C., & Raught, B. (2012) · FEBS Letters

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 34

Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers

Abe, K. T., Hu, Q., Mozafarihashjin, M., Samson, R., Manguiat, K., Robinson, A., Rathod, B., Hardy, W. R., Wang, J. H., Iskilova, M., et al. (2021) · medRxiv

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 32

Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs

Nishimura, T., Fakim, H., Brandmann, T., Youn, J.-Y., Gingras, A.-C., Jinek, M., & Fabian, M. R. (2018) · Nucleic Acids Research

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 31

CLMSVault: A software suite for protein cross-linking mass-spectrometry data analysis and visualization

Courcelles, M., Coulombe-Huntington, J., Cossette, É., Gingras, A.-C., Thibault, P., & Tyers, M. (2017) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 21

Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring

Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Del Corpo, J., Zou, D., Morin, G., et al. (2024) · Cell Reports

Cancer Genomics and DiagnosticsBreast Cancer Treatment Studies

Cited by 20