Daskalakis, Nikolaos P.

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation

Yehuda, R., Daskalakis, N. P., Bierer, L. M., Bader, H. N., Klengel, T., Holsboer, F., & Binder, E. B. (2016) · Biological Psychiatry

Epigenetics and DNA MethylationPosttraumatic Stress Disorder Research

Cited by 782

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., et al. (2019) · Nature Communications

Posttraumatic Stress Disorder ResearchGenetic Associations and Epidemiology

Cited by 635

The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome

Daskalakis, N. P., Bagot, R. C., Parker, K. J., Vinkers, C. H., & de Kloet, E. R. (2013) · Psychoneuroendocrinology

Stress Responses and CortisolResilience and Mental Health

Cited by 579

Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring

Yehuda, R., Daskalakis, N. P., Lehrner, A., Desarnaud, F., Bader, H. N., Makotkine, I., Flory, J. D., Bierer, L. M., & Meaney, M. J. (2014) · American Journal of Psychiatry

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 514

Epigenetic biomarkers as predictors and correlates of symptom improvement following psychotherapy in combat veterans with PTSD

Yehuda, R., Daskalakis, N. P., Desarnaud, F., Makotkine, I., Lehrner, A. L., Koch, E., Flory, J. D., Buxbaum, J. D., Meaney, M. J., & Bierer, L. M. (2013) · Frontiers in Psychiatry

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

Cited by 358

Lower Methylation of Glucocorticoid Receptor Gene Promoter 1F in Peripheral Blood of Veterans with Posttraumatic Stress Disorder

Yehuda, R., Flory, J. D., Bierer, L. M., Henn-Haase, C., Lehrner, A., Desarnaud, F., Makotkine, I., Daskalakis, N. P., Marmar, C. R., & Meaney, M. J. (2015) · Biological Psychiatry

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 293

Defeat stress in rodents: from behavior to molecules

Hammels, C., Pishva, E., De Vry, J., van den Hove, D. L. A., Prickaerts, J., van Winkel, R., Selten, J.-P., Lesch, K.-P., Daskalakis, N. P., Steinbusch, H. W. M., et al. (2015) · Neuroscience & Biobehavioral Reviews

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 230

Endocrine aspects of post-traumatic stress disorder and implications for diagnosis and treatment

Daskalakis, N. P., Lehrner, A., & Yehuda, R. (2013) · Endocrinology and Metabolism Clinics of North America

Stress Responses and CortisolPosttraumatic Stress Disorder Research

Cited by 209

Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

Harony-Nicolas, H., Kay, M., Hoffmann, J. D., Klein, M. E., Bozdagi-Gunal, O., Riad, M., Daskalakis, N. P., Sonar, S., Castillo, P. E., Hof, P. R., et al. (2017) · eLife

Genetics and Neurodevelopmental DisordersNeuroendocrine regulation and behavior

Cited by 168

Maternal PTSD associates with greater glucocorticoid sensitivity in offspring of Holocaust survivors

Lehrner, A., Bierer, L. M., Passarelli, V., Pratchett, L. C., Flory, J. D., Bader, H. N., Harris, I. R., Bedi, A., Daskalakis, N. P., Makotkine, I., et al. (2014) · Psychoneuroendocrinology

Stress Responses and CortisolPosttraumatic Stress Disorder Research

Cited by 160

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

Rutten, B. P. F., Vermetten, E., Vinkers, C. H., Ursini, G., Daskalakis, N. P., Pishva, E., de Nijs, L., Houtepen, L. C., Eijssen, L., Jaffe, A. E., et al. (2018) · Molecular Psychiatry

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

Cited by 142

Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5

Hartmann, J., Bajaj, T., Klengel, C., Chatzinakos, C., Ebert, T., Dedic, N., McCullough, K. M., Lardenoije, R., Joëls, M., Meijer, O. C., et al. (2021) · Cell Reports

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 119

Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: Systematic review of contributing factors

Daskalakis, N. P., & Yehuda, R. (2014) · Frontiers in Neuroscience

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 108

New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility

Daskalakis, N. P., Cohen, H., Nievergelt, C. M., Baker, D. G., Buxbaum, J. D., Russo, S. J., & Yehuda, R. (2016) · Experimental Neurology

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 105

Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation

Bierer, L. M., Bader, H. N., Daskalakis, N. P., Lehrner, A., Provençal, N., Wiechmann, T., Klengel, T., Makotkine, I., Binder, E. B., & Yehuda, R. (2020) · American Journal of Psychiatry

Epigenetics and DNA MethylationPosttraumatic Stress Disorder Research

Cited by 86

Oxidative Dysregulation in Early Life Stress and Posttraumatic Stress Disorder: A Comprehensive Review

Karanikas, E., Daskalakis, N. P., & Agorastos, A. (2021) · Brain Sciences

Posttraumatic Stress Disorder ResearchRedox biology and oxidative stress

Cited by 78

Elevation of 11β-hydroxysteroid dehydrogenase type 2 activity in Holocaust survivor offspring: Evidence for an intergenerational effect of maternal trauma exposure

Bierer, L. M., Bader, H. N., Daskalakis, N. P., Lehrner, A. L., Makotkine, I., Seckl, J. R., & Yehuda, R. (2014) · Psychoneuroendocrinology

Stress Responses and CortisolPosttraumatic Stress Disorder Research

Cited by 57

Maternal Age at Holocaust Exposure and Maternal PTSD Independently Influence Urinary Cortisol Levels in Adult Offspring

Bader, H. N., Bierer, L. M., Lehrner, A., Makotkine, I., Daskalakis, N. P., & Yehuda, R. (2014) · Frontiers in Endocrinology

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 36

Longitudinal changes in glucocorticoid receptor exon 1F methylation and psychopathology after military deployment

Schür, R. R., Boks, M. P., Rutten, B. P. F., Daskalakis, N. P., de Nijs, L., van Zuiden, M., Kavelaars, A., Heijnen, C. J., Joëls, M., Kahn, R. S., et al. (2017) · Translational Psychiatry

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

Cited by 31