Adams, Jerry M.

The Bcl2 family: regulators of the cellular life-or-death switch

Cory, S., & Adams, J. M. (2002) · Nature Reviews Cancer

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 4,032

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

Czabotar, P. E., Lessene, G., Strasser, A., & Adams, J. M. (2014) · Nature Reviews Molecular Cell Biology

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 3,219

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Chen, L., Willis, S. N., Wei, A., Smith, B. J., Fletcher, J. I., Hinds, M. G., Colman, P. M., Day, C. L., Adams, J. M., & Huang, D. C. S. (2005) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,816

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Bouillet, P., Metcalf, D., Huang, D. C. S., Tarlinton, D. M., Kay, T. W. H., Köntgen, F., Adams, J. M., & Strasser, A. (1999) · Science

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 1,504

p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

Villunger, A., Michalak, E. M., Coultas, L., Müllauer, F., Böck, G., Ausserlechner, M. J., Adams, J. M., & Strasser, A. (2003) · Science

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,327

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Bouillet, P., Purton, J. F., Godfrey, D. I., Zhang, L.-C., Coultas, L., Puthalakath, H., Pellegrini, M., Cory, S., Adams, J. M., & Strasser, A. (2002) · Nature

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 782

Life in the balance: how BH3-only proteins induce apoptosis

Willis, S. N., & Adams, J. M. (2005) · Current Opinion in Cell Biology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 743

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Marsden, V. S., O'Connor, L., O'Reilly, L. A., Silke, J., Metcalf, D., Ekert, P. G., Huang, D. C. S., Cecconi, F., Kuida, K., Tomaselli, K. J., et al. (2002) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 578

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

Czabotar, P. E., Westphal, D., Dewson, G., Ma, S., Hockings, C., Fairlie, W. D., Lee, E. F., Yao, S., Robin, A. Y., Smith, B. J., et al. (2013) · Cell

Cell death mechanisms and regulationEnzyme Structure and Function

Cited by 573

The BCL-2 arbiters of apoptosis and their growing role as cancer targets

Adams, J. M., & Cory, S. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 530

Killing cancer cells by flipping the Bcl-2/Bax switch

Cory, S., & Adams, J. M. (2005) · Cancer Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 217

GATA‐1 but not SCL induces megakaryocytic differentiation in an early myeloid line.

Visvader, J. E., Elefanty, A. G., Strasser, A., & Adams, J. M. (1992) · The EMBO Journal

Platelet Disorders and TreatmentsHematopoietic Stem Cell Transplantation

Cited by 189

The C-Terminal Zinc Finger of GATA-1 or GATA-2 Is Sufficient To Induce Megakaryocytic Differentiation of an Early Myeloid Cell Line

Visvader, J. E., Crossley, M., Hill, J., Orkin, S. H., & Adams, J. M. (1995) · Molecular and Cellular Biology

Platelet Disorders and TreatmentsGenomics and Chromatin Dynamics

Cited by 151

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain

Cook, W. D., McCaw, B. J., Herring, C., John, D. L., Foote, S. J., Nutt, S. L., & Adams, J. M. (2004) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 140

Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells

Naik, E., O'Reilly, L. A., Asselin-Labat, M.-L., Merino, D., Lin, A., Cook, M., Coultas, L., Bouillet, P., Adams, J. M., & Strasser, A. (2011) · Journal of Experimental Medicine

Angiogenesis and VEGF in CancerCell death mechanisms and regulation

Cited by 31