Nguyen, Hannah

Robust deep learning–based protein sequence design using ProteinMPNN

Dauparas, J., Anishchenko, I., Bennett, N., Bai, H., Ragotte, R. J., Milles, L. F., Wicky, B. I. M., Courbet, A., de Haas, R. J., Bethel, N., et al. (2022) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 2,210

Robust deep learning based protein sequence design using ProteinMPNN

Dauparas, J., Anishchenko, I., Bennett, N., Bai, H., Ragotte, R. J., Milles, L. F., Wicky, B. I. M., Courbet, A., de Haas, R. J., Bethel, N., et al. (2022) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 2,107

Hallucinating symmetric protein assemblies

Wicky, B. I. M., Milles, L. F., Courbet, A., Ragotte, R. J., Dauparas, J., Kinfu, E., Tipps, S., Kibler, R. D., Baek, M., DiMaio, F., et al. (2022) · Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 240

Hallucinating protein assemblies

Wicky, B. I. M., Milles, L. F., Courbet, A., Ragotte, R. J., Dauparas, J., Kinfu, E., Tipps, S., Kibler, R. D., Baek, M., DiMaio, F., et al. (2022) · Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 240

Design of stimulus-responsive two-state hinge proteins

Praetorius, F., Leung, P. J. Y., Tessmer, M. H., Broerman, A., Demakis, C., Dishman, A. F., Pillai, A., Idris, A., Juergens, D., Dauparas, J., et al. (2023) · Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 90

Design of stimulus-responsive two-state hinge proteins

Praetorius, F., Leung, P. J. Y., Tessmer, M. H., Broerman, A., Demakis, C., Dishman, A. F., Pillai, A., Idris, A., Juergens, D., Dauparas, J., et al. (2023) · Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 90

Design of amyloidogenic peptide traps

Sahtoe, D. D., Andrzejewska, E. A., Han, H. L., Rennella, E., Schneider, M. M., Meisl, G., Ahlrichs, M., Decarreau, J., Nguyen, H., Kang, A., et al. (2024) · Nature Chemical Biology

Alzheimer's disease research and treatmentsProtein Structure and Dynamics

Cited by 48

Design of amyloidogenic peptide traps

Sahtoe, D. D., Andrzejewska, E. A., Han, H. L., Rennella, E., Schneider, M. M., Meisl, G., Ahlrichs, M., Decarreau, J., Nguyen, H., Kang, A., et al. (2023) · Nature Chemical Biology

Alzheimer's disease research and treatmentsProtein Structure and Dynamics

Cited by 48

Rapid and automated design of two-component protein nanomaterials using ProteinMPNN

de Haas, R. J., Brunette, N., Goodson, A., Dauparas, J., Yi, S. Y., Yang, E. C., Dowling, Q., Nguyen, H., Kang, A., Bera, A. K., et al. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 42

Rapid and automated design of two-component protein nanomaterials using ProteinMPNN

de Haas, R. J., Brunette, N., Goodson, A., Dauparas, J., Yi, S. Y., Yang, E. C., Dowling, Q., Nguyen, H., Kang, A., Bera, A. K., et al. (2023) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 42

Small-molecule binding and sensing with a designed protein family

Lee, G. R., Pellock, S. J., Norn, C., Tischer, D., Dauparas, J., Anischenko, I., Mercer, J. A. M., Kang, A., Bera, A., Nguyen, H., et al. (2023) · Nature Communications

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 41

Hallucination of closed repeat proteins containing central pockets

An, L., Hicks, D. R., Zorine, D., Dauparas, J., Wicky, B. I. M., Milles, L. F., Courbet, A., Bera, A. K., Nguyen, H., Kang, A., et al. (2023) · Nature Structural & Molecular Biology

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 15

Hallucination of closed repeat proteins containing central pockets

An, L., Hicks, D. R., Zorine, D., Dauparas, J., Wicky, B. I. M., Milles, L. F., Courbet, A., Bera, A. K., Nguyen, H., Kang, A., et al. (2022) · Nature Structural & Molecular Biology

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 15

De novo designed ice-binding proteins from twist-constrained helices

de Haas, R. J., Tas, R. P., van den Broek, D., Nguyen, H., Kang, A., Bera, A. K., King, N. P., Voets, I. K., & de Vries, R. (2022) · Proceedings of the National Academy of Sciences

Protein Structure and Dynamicsnanoparticles nucleation surface interactions

Cited by 12

De novo designed ice-binding proteins from twist-constrained helices

de Haas, R. J., Tas, R. P., van den Broek, D., Zheng, C., Nguyen, H., Kang, A., Bera, A. K., King, N. P., Voets, I. K., & de Vries, R. (2023) · Proceedings of the National Academy of Sciences

Protein Structure and Dynamicsnanoparticles nucleation surface interactions

Cited by 12