Mummery, Christine L.

Organs-on-chips: into the next decade

Low, L. A., Mummery, C., Berridge, B. R., Austin, C. P., & Tagle, D. A. (2021) · Nature Reviews Drug Discovery

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 1,029

Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture With Visceral Endoderm-Like Cells

Mummery, C., Ward-van Oostwaard, D., Doevendans, P., Spijker, R., van den Brink, S., Hassink, R., van der Heyden, M., Opthof, T., Pera, M., de la Riviere, A. B., et al. (2003) · Circulation

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 1,001

Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

Goumans, M.-J., Valdimarsdottir, G., Itoh, S., Lebrin, F., Larsson, J., Mummery, C., Karlsson, S., & ten Dijke, P. (2003) · Molecular Cell

TGF-β signaling in diseasesDevelopmental Biology and Gene Regulation

Cited by 689

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

Giacomelli, E., Meraviglia, V., Campostrini, G., Cochrane, A., Cao, X., van Helden, R. W. J., Krotenberg Garcia, A., Mircea, M., Kostidis, S., Davis, R. P., et al. (2020) · Cell Stem Cell

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 622

Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice

Larsson, J., Goumans, M., Sjöstrand, L. J., van Rooijen, M. A., Ward, D., Levéen, P., Xu, X., ten Dijke, P., Mummery, C. L., & Karlsson, S. (2001) · The EMBO Journal

TGF-β signaling in diseasesAngiogenesis and VEGF in Cancer

Cited by 563

Small molecule absorption by PDMS in the context of drug response bioassays

van Meer, B. J., de Vries, H., Firth, K. S. A., van Weerd, J., Tertoolen, L. G. J., Karperien, H. B. J., Jonkheijm, P., Denning, C., IJzerman, A. P., & Mummery, C. L. (2017) · Biochemical and Biophysical Research Communications

Microfluidic and Capillary Electrophoresis Applications3D Printing in Biomedical Research

Cited by 502

NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

Elliott, D. A., Braam, S. R., Koutsis, K., Ng, E. S., Jenny, R., Lagerqvist, E. L., Biben, C., Hatzistavrou, T., Hirst, C. E., Yu, Q. C., et al. (2011) · Nature Methods

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 426

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

Sala, L., van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., et al. (2018) · Circulation Research

Cardiac electrophysiology and arrhythmiasCardiovascular Function and Risk Factors

Cited by 416

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

Orlova, V. V., van den Hil, F. E., Petrus-Reurer, S., Drabsch, Y., ten Dijke, P., & Mummery, C. L. (2014) · Nature Protocols

Pluripotent Stem Cells ResearchAngiogenesis and VEGF in Cancer

Cited by 365

FANTOM5 CAGE profiles of human and mouse samples

Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., et al. (2017) · Scientific Data

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 310

Personalised organs-on-chips: functional testing for precision medicine

van den Berg, A., Mummery, C. L., Passier, R., & van der Meer, A. D. (2019) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 270

Isl1Cre reveals a common Bmp pathway in heart and limb development

Yang, L., Cai, C.-L., Lin, L., Qyang, Y., Chung, C., Monteiro, R. M., Mummery, C. L., Fishman, G. I., Cogen, A., & Evans, S. (2006) · Development

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 267

Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro–correlation between contraction force and electrophysiology

Ribeiro, M. C., Tertoolen, L. G., Guadix, J. A., Bellin, M., Kosmidis, G., D'Aniello, C., Monshouwer-Kloots, J., Goumans, M.-J., Wang, Y.-L., Feinberg, A. W., et al. (2015) · Biomaterials

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 214

Complex Tissue and Disease Modeling using hiPSCs

Passier, R., Orlova, V., & Mummery, C. (2016) · Cell Stem Cell

Pluripotent Stem Cells Research3D Printing in Biomedical Research

Cited by 142

ISSCR standards for the use of human stem cells in basic research

Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., et al. (2023) · Stem Cell Reports

Pluripotent Stem Cells ResearchBiomedical Ethics and Regulation

Cited by 126

Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and electrical membrane properties during the cell cycle

Boonstra, J., Mummery, C. L., Tertoolen, L. G. J., Van Der Saag, P. T., & De Laat, S. W. (1981) · Journal of Cellular Physiology

Ion channel regulation and functionIon Transport and Channel Regulation

Cited by 108

Cardiac Tissues From Stem Cells: New Routes to Maturation and Cardiac Regeneration

Campostrini, G., Windt, L. M., van Meer, B. J., Bellin, M., & Mummery, C. L. (2021) · Circulation Research

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 96

Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery

Braam, S. R., Passier, R., & Mummery, C. L. (2009) · Trends in Pharmacological Sciences

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 86

Vascularized hiPSC-derived 3D cardiac microtissue on chip

Arslan, U., Brescia, M., Meraviglia, V., Nahon, D. M., van Helden, R. W. J., Stein, J. M., van den Hil, F. E., van Meer, B. J., Vila Cuenca, M., Mummery, C. L., et al. (2023) · Stem Cell Reports

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 66

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

Roost, M. S., Slieker, R. C., Bialecka, M., van Iperen, L., Gomes Fernandes, M. M., He, N., Suchiman, H. E. D., Szuhai, K., Carlotti, F., de Koning, E. J. P., et al. (2017) · Nature Communications

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 65

Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes

Giacomelli, E., Mummery, C. L., & Bellin, M. (2017) · Cellular and Molecular Life Sciences

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 60

Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids

Ramovs, V., Janssen, H., Fuentes, I., Pitaval, A., Rachidi, W., Chuva de Sousa Lopes, S. M., Freund, C., Gidrol, X., Mummery, C. L., & Raymond, K. (2022) · Stem Cell Reports

Skin and Cellular Biology ResearchHair Growth and Disorders

Cited by 44

Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells

Pistollato, F., Bal-Price, A., Coecke, S., Parvatam, S., Pamies, D., Czysz, K., Hao, J., Kee, K., Teo, A. K. K., Niu, S., et al. (2022) · Reproductive Toxicology

Pluripotent Stem Cells ResearchAnimal testing and alternatives

Cited by 10