Vallon, Volker

(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms

Lang, F., Böhmer, C., Palmada, M., Seebohm, G., Strutz-Seebohm, N., & Vallon, V. (2006) · Physiological Reviews

Ion Transport and Channel RegulationIon channel regulation and function

Cited by 689

Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

Gorboulev, V., Schürmann, A., Vallon, V., Kipp, H., Jaschke, A., Klessen, D., Friedrich, A., Scherneck, S., Rieg, T., Cunard, R., et al. (2012) · Diabetes

Diabetes Treatment and ManagementIon Transport and Channel Regulation

Cited by 687

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition

Vallon, V., & Thomson, S. C. (2017) · Diabetologia

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 635

SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice

Vallon, V., Gerasimova, M., Rose, M. A., Masuda, T., Satriano, J., Mayoux, E., Koepsell, H., Thomson, S. C., & Rieg, T. (2014) · American Journal of Physiology-Renal Physiology

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 483

The tubular hypothesis of nephron filtration and diabetic kidney disease

Vallon, V., & Thomson, S. C. (2020) · Nature Reviews Nephrology

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 465

Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences

Gallo, L. A., Wright, E. M., & Vallon, V. (2015) · Diabetes and Vascular Disease Research

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 395

Development of SGLT1 and SGLT2 inhibitors

Rieg, T., & Vallon, V. (2018) · Diabetologia

Diabetes Treatment and ManagementIon Transport and Channel Regulation

Cited by 377

Renal Function in Diabetic Disease Models: The Tubular System in the Pathophysiology of the Diabetic Kidney

Vallon, V., & Thomson, S. C. (2012) · Annual Review of Physiology

Chronic Kidney Disease and DiabetesRenal Diseases and Glomerulopathies

Cited by 376

Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

Vallon, V., Rose, M., Gerasimova, M., Satriano, J., Platt, K. A., Koepsell, H., Cunard, R., Sharma, K., Thomson, S. C., & Rieg, T. (2013) · American Journal of Physiology-Renal Physiology

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 370

Multiple organic anion transporters contribute to net renal excretion of uric acid

Eraly, S. A., Vallon, V., Rieg, T., Gangoiti, J. A., Wikoff, W. R., Siuzdak, G., Barshop, B. A., & Nigam, S. K. (2008) · Physiological Genomics

Gout, Hyperuricemia, Uric AcidDrug Transport and Resistance Mechanisms

Cited by 235

A role for tubular Na+/H+exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin

Onishi, A., Fu, Y., Patel, R., Darshi, M., Crespo-Masip, M., Huang, W., Song, P., Freeman, B., Kim, Y. C., Soleimani, M., et al. (2020) · American Journal of Physiology-Renal Physiology

Ion Transport and Channel RegulationDiabetes Treatment and Management

Cited by 206

The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?

Hesp, A. C., Schaub, J. A., Prasad, P. V., Vallon, V., Laverman, G. D., Bjornstad, P., & van Raalte, D. H. (2020) · Kidney International

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 202

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

Novikov, A., Fu, Y., Huang, W., Freeman, B., Patel, R., van Ginkel, C., Koepsell, H., Busslinger, M., Onishi, A., Nespoux, J., et al. (2019) · American Journal of Physiology-Renal Physiology

Gout, Hyperuricemia, Uric AcidIon Transport and Channel Regulation

Cited by 186

The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

Lang, F., Artunc, F., & Vallon, V. (2009) · Current Opinion in Nephrology and Hypertension

Ion Transport and Channel RegulationRenin-Angiotensin System Studies

Cited by 139

Requirement of Intact Adenosine A1 Receptors for the Diuretic and Natriuretic Action of the Methylxanthines Theophylline and Caffeine

Rieg, T., Steigele, H., Schnermann, J., Richter, K., Osswald, H., & Vallon, V. (2005) · The Journal of Pharmacology and Experimental Therapeutics

Adenosine and Purinergic SignalingIon Transport and Channel Regulation

Cited by 133

SGLT2 inhibition in a kidney with reduced nephron number: modeling and analysis of solute transport and metabolism

Layton, A. T., & Vallon, V. (2018) · American Journal of Physiology-Renal Physiology

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 132

SGLT2 inhibition for CKD and cardiovascular disease in type 2 diabetes: report of a scientific workshop sponsored by the National Kidney Foundation

Tuttle, K. R., Brosius, F. C., Cavender, M. A., Fioretto, P., Fowler, K. J., Heerspink, H. J. L., Manley, T., McGuire, D. K., Molitch, M. E., Mottl, A. K., et al. (2021) · Diabetes

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 123

Homeostatic efficiency of tubuloglomerular feedback is reduced in established diabetes mellitus in rats

Vallon, V., Blantz, R. C., & Thomson, S. (1995) · American Journal of Physiology-Renal Physiology

Chronic Kidney Disease and DiabetesBlood Pressure and Hypertension Studies

Cited by 112

Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis

Hallow, K. M., Gebremichael, Y., Helmlinger, G., & Vallon, V. (2017) · American Journal of Physiology-Renal Physiology

Chronic Kidney Disease and DiabetesIon Transport and Channel Regulation

Cited by 98

Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes

Satriano, J., Mansoury, H., Deng, A., Sharma, K., Vallon, V., Blantz, R. C., & Thomson, S. C. (2010) · American Journal of Physiology-Cell Physiology

Chronic Kidney Disease and DiabetesTelomeres, Telomerase, and Senescence

Cited by 93

Effect of renal tubule-specific knockdown of the Na+/H+exchanger NHE3 in Akita diabetic mice

Onishi, A., Fu, Y., Darshi, M., Crespo-Masip, M., Huang, W., Song, P., Patel, R., Kim, Y. C., Nespoux, J., Freeman, B., et al. (2019) · American Journal of Physiology-Renal Physiology

Ion Transport and Channel RegulationChronic Kidney Disease and Diabetes

Cited by 71