Young, Stephen G.

Lamin B1 is required for mouse development and nuclear integrity

Vergnes, L., Péterfy, M., Bergo, M. O., Young, S. G., & Reue, K. (2004) · Proceedings of the National Academy of Sciences

Nuclear Structure and FunctionSkin and Cellular Biology Research

Cited by 391

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

Linton, M. F., Gish, R., Hubl, S. T., Bütler, E., Esquivel, C., Bry, W. I., Boyles, J. K., Wardell, M. R., & Young, S. G. (1991) · Journal of Clinical Investigation

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 367

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

Sandhu, J., Li, S., Fairall, L., Pfisterer, S. G., Gurnett, J. E., Xiao, X., Weston, T. A., Vashi, D., Ferrari, A., Orozco, J. L., et al. (2018) · Cell

Cholesterol and Lipid MetabolismCellular transport and secretion

Cited by 287

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

Coffinier, C., Jung, H.-J., Nobumori, C., Chang, S., Tu, Y., Barnes, R. H., Yoshinaga, Y., de Jong, P. J., Vergnes, L., Reue, K., et al. (2011) · Molecular Biology of the Cell

Nuclear Structure and FunctionNeurogenesis and neuroplasticity mechanisms

Cited by 225

Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

Bergo, M. O., Gavino, B. J., Hong, C., Beigneux, A. P., McMahon, M., Casey, P. J., & Young, S. G. (2004) · Journal of Clinical Investigation

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 180

A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells

Winter-Vann, A. M., Baron, R. A., Wong, W., dela Cruz, J., York, J. D., Gooden, D. M., Bergo, M. O., Young, S. G., Toone, E. J., & Casey, P. J. (2005) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingCancer-related gene regulation

Cited by 178

Feedback Regulation of Cholesterol Uptake by the LXR–IDOL–LDLR Axis

Zhang, L., Reue, K., Fong, L. G., Young, S. G., & Tontonoz, P. (2012) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 137

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia.

Olivecrona, G., Ehrenborg, E., Semb, H., Makoveichuk, E., Lindberg, A., Hayden, M. R., Gin, P., Davies, B. S. J., Weinstein, M. M., Fong, L. G., et al. (2010) · Journal of Lipid Research

Lipid metabolism and disordersLymphatic Disorders and Treatments

Cited by 118

Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

Véniant, M. M., Pierotti, V, Newland, D., Cham, C. M., Sanan, D. A., Walzem, R. L., & Young, S. G. (1997) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 100

The LXR–Idol Axis Differentially Regulates Plasma LDL Levels in Primates and Mice

Hong, C., Marshall, S. M., McDaniel, A. L., Graham, M., Layne, J. D., Cai, L., Scotti, E., Boyadjian, R., Kim, J., Chamberlain, B. T., et al. (2014) · Cell Metabolism

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 87

The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.

Gin, P., Yin, L., Davies, B. S. J., Weinstein, M. M., Ryan, R. O., Bensadoun, A., Fong, L. G., Young, S. G., & Beigneux, A. P. (2008) · Journal of Biological Chemistry

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 85

Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists

Scotti, E., Hong, C., Yoshinaga, Y., Tu, Y., Hu, Y., Zelcer, N., Boyadjian, R., de Jong, P. J., Young, S. G., Fong, L. G., et al. (2011) · Molecular and Cellular Biology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 77

Chylomicronemia elicits atherosclerosis in mice—brief report.

Weinstein, M. M., Yin, L., Tu, Y., Wang, X., Wu, X., Castellani, L. W., Walzem, R. L., Lusis, A. J., Fong, L. G., Beigneux, A. P., et al. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 71

Lipoprotein size and susceptibility to atherosclerosis—insights from genetically modified mouse models.

Young, S., Veniant, M., Beigneux, A., Bensadoun, A., & Fong, L. (2008) · Current Drug Targets

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 33

Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling

MacKay, K. B., Tu, Y., Young, S. G., & Clarke, S. G. (2013) · PLoS ONE

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 14