Hartl, F. Ulrich

The proteostasis network and its decline in ageing

Hipp, M. S., Kasturi, P., & Hartl, F. U. (2019) · Nature Reviews Molecular Cell Biology

Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms

Cited by 1,642

Structure of TPR Domain–Peptide Complexes

Scheufler, C., Brinker, A., Bourenkov, G., Pegoraro, S., Moroder, L., Bartunik, H., Hartl, F. U., & Moarefi, I. (2000) · Cell

Heat shock proteins researchProtein Structure and Dynamics

Cited by 1,188

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

Young, J. C., Hoogenraad, N. J., & Hartl, F. U. (2003) · Cell

Heat shock proteins researchMitochondrial Function and Pathology

Cited by 915

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, D. M., Kasturi, P., Zheng, M., Pinkert, S., Vecchi, G., Ciryam, P., Morimoto, R. I., Dobson, C. M., Vendruscolo, M., Mann, M., et al. (2015) · Cell

Genetics, Aging, and Longevity in Model OrganismsHeat shock proteins research

Cited by 569

The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane

Hartl, F.-U., Lecker, S., Schiebel, E., Hendrick, J. P., & Wickner, W. (1990) · Cell

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 562

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

Gamerdinger, M., Hajieva, P., Kaya, A. M., Wolfrum, U., Hartl, F. U., & Behl, C. (2009) · The EMBO Journal

Autophagy in Disease and TherapyHeat shock proteins research

Cited by 522

Polypeptide Flux through Bacterial Hsp70

Teter, S. A., Houry, W. A., Ang, D., Tradler, T., Rockabrand, D., Fischer, G., Blum, P., Georgopoulos, C., & Hartl, F. U. (1999) · Cell

Heat shock proteins researchBacterial Genetics and Biotechnology

Cited by 424

A Balance of Protein Synthesis and Proteasome-Dependent Degradation Determines the Maintenance of LTP

Fonseca, R., Vabulas, R. M., Hartl, F. U., Bonhoeffer, T., & Nägerl, U. V. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 310

The native 3D organization of bacterial polysomes

Brandt, F., Etchells, S. A., Ortiz, J. O., Elcock, A. H., Hartl, F. U., & Baumeister, W. (2009) · Cell

RNA and protein synthesis mechanismsAdvanced Electron Microscopy Techniques and Applications

Cited by 258

Firefly luciferase mutants as sensors of proteome stress

Gupta, R., Kasturi, P., Bracher, A., Loew, C., Zheng, M., Villella, A., Garza, D., Hartl, F. U., & Raychaudhuri, S. (2011) · Nature Methods

Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms

Cited by 219

Structure and function of the AAA+ protein CbbX, a red-type Rubisco activase

Mueller-Cajar, O., Stotz, M., Wendler, P., Hartl, F. U., Bracher, A., & Hayer-Hartl, M. (2011) · Nature

Photosynthetic Processes and MechanismsEnzyme Structure and Function

Cited by 190

Structural analyses define the molecular basis of clusterin chaperone function

Yuste-Checa, P., Carvajal, A. I., Mi, C., Paatz, S., Hartl, F. U., & Bracher, A. (2025) · Nature Structural & Molecular Biology

Clusterin in disease pathologyHeat shock proteins research

Cited by 18

Autophagy preferentially degrades non-fibrillar polyQ aggregates

Zhao, D. Y., Bäuerlein, F. J. B., Saha, I., Hartl, F. U., Baumeister, W., & Wilfling, F. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 3