Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

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Structure of a Bag/Hsc70 Complex: Convergent Functional Evolution of Hsp70 Nucleotide Exchange Factors

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A mitochondrial import receptor for the ADP/ATP carrier

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Differential Recognition of Preproteins by the Purified Cytosolic Domains of the Mitochondrial Import Receptors Tom20, Tom22, and Tom70

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Preprotein Translocase of the Outer Mitochondrial Membrane: Molecular Dissection and Assembly of the General Import Pore Complex

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The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

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Distinct steps in the import of ADP/ATP carrier into mitochondria.

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Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co‐chaperone p23

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Specific Binding of Tetratricopeptide Repeat Proteins to the C-terminal 12-kDa Domain of hsp90

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Ligand Discrimination by TPR Domains

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Functional cooperation of mitochondrial protein import receptors in yeast.

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Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria.

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Role of the ABC Transporter Mdl1 in Peptide Export from Mitochondria

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Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22·54 complex

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Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

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Functional Staging of ADP/ATP Carrier Translocation across the Outer Mitochondrial Membrane

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Import and assembly of proteins into mitochondria of mammalian cells

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MSF, a novel cytoplasmic chaperone which functions in precursor targeting to mitochondria.

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The mitochondrial import receptor Tom70: identification of a 25 kda core domain with a specific binding site for preproteins 1 1Edited by M. Yaniv

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The cleavable presequence is not essential for import and assembly of the phosphate carrier of mammalian mitochondria but enhances the specificity and efficiency of import.

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Prediction of Novel Bag-1 Homologs Based on Structure/Function Analysis Identifies Snl1p as an Hsp70 Co-chaperone in Saccharomyces cerevisiae

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Characterization of rat TOM70 as a receptor of the preprotein translocase of the mitochondrial outer membrane

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Effect of deletions within the leader peptide of pre‐ornithine transcarbamylase on mitochondrial import

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Expanding the Eukaryote's Cast of Chaperones

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HSP90 at the hub of protein homeostasis: emerging mechanistic insights

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The proteostasis network and its decline in ageing

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Structure and mechanism of the Hsp90 molecular chaperone machinery

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Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

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Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer’s disease

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Mitochondrial protein import: from proteomics to functional mechanisms

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HSP72 protects against obesity-induced insulin resistance

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The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones

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The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

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The Protein Import Machinery of Mitochondria

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Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement

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Under cover: causes, effects and implications of Hsp90‐mediated genetic capacitance

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Firefly luciferase mutants as sensors of proteome stress

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Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

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HSP90AB1: Helping the good and the bad

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A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).

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Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells

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Roles of Tom70 in Import of Presequence-containing Mitochondrial Proteins

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RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress

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Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease

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Mitochondrial protein import and the genesis of steroidogenic mitochondria

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In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy

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Coupling of import and assembly pathways in mitochondrial protein biogenesis

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Suppression of a Defect in Mitochondrial Protein Import Identifies Cytosolic Proteins Required for Viability of Yeast Cells Lacking Mitochondrial DNA

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Mitochondrial stress-dependent regulation of cellular protein synthesis

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The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit

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Oxidation-driven protein import into mitochondria: Insights and blind spots

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Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?

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Effect of age on the processing and import of matrix-destined mitochondrial proteins in skeletal muscle

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Geldanamycin confers fungicidal properties to azole by triggering the activation of succinate dehydrogenase

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Author Index for Volume 72

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Targeting of proteins to mitochondria

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Protein insertion into the inner membrane of mitochondria: routes and mechanisms

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How lipids modulate mitochondrial protein import

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Mechanisms of protein translocation into mitochondria

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