Lei, Qun-Ying

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Xu, W., Yang, H., Liu, Y., Yang, Y., Wang, P., Kim, S.-H., Ito, S., Yang, C., Wang, P., Xiao, M.-T., et al. (2011) · Cancer Cell

Glioma Diagnosis and TreatmentEpigenetics and DNA Methylation

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The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase

Liu, C.-Y., Zha, Z.-Y., Zhou, X., Zhang, H., Huang, W., Zhao, D., Li, T., Chan, S. W., Lim, C. J., Hong, W., et al. (2010) · Journal of Biological Chemistry

Hippo pathway signaling and YAP/TAZUbiquitin and proteasome pathways

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Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth

Lin, R., Tao, R., Gao, X., Li, T., Zhou, X., Guan, K.-L., Xiong, Y., & Lei, Q.-Y. (2013) · Molecular Cell

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

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Estrogen regulates Hippo signaling via GPER in breast cancer

Zhou, X., Wang, S., Wang, Z., Feng, X., Liu, P., Lv, X.-B., Li, F., Yu, F.-X., Sun, Y., Yuan, H., et al. (2015) · Journal of Clinical Investigation

Hippo pathway signaling and YAP/TAZEstrogen and related hormone effects

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Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth

Lei, M.-Z., Li, X.-X., Zhang, Y., Li, J.-T., Zhang, F., Wang, Y.-P., Yin, M., Qu, J., & Lei, Q.-Y. (2020) · Signal Transduction and Targeted Therapy

Cancer, Lipids, and MetabolismPancreatic and Hepatic Oncology Research

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Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth

Fan, J., Lin, R., Xia, S., Chen, D., Elf, S. E., Liu, S., Pan, Y., Xu, H., Qian, Z., Wang, M., et al. (2016) · Molecular Cell

Cancer, Hypoxia, and MetabolismBiochemical Acid Research Studies

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Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer

Yang, H.-B., Xu, Y.-Y., Zhao, X.-N., Zou, S.-W., Zhang, Y., Zhang, M., Li, J.-T., Ren, F., Wang, L.-Y., & Lei, Q.-Y. (2015) · Nature Communications

Cancer-related gene regulationUbiquitin and proteasome pathways

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YAP/TAZ mediates resistance to KRAS inhibitors through inhibiting proapoptosis and activating the SLC7A5/mTOR axis

Yang, W., Zhang, M., Zhang, T.-X., Liu, J.-H., Hao, M.-W., Yan, X., Gao, H., Lei, Q.-Y., Cui, J., & Zhou, X. (2024) · JCI Insight

Hippo pathway signaling and YAP/TAZProtein Kinase Regulation and GTPase Signaling

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