Dörken, Bernd

Oncogene-induced senescence as an initial barrier in lymphoma development

Braig, M., Lee, S., Loddenkemper, C., Rudolph, C., Peters, A. H. F. M., Schlegelberger, B., Stein, H., Dörken, B., Jenuwein, T., & Schmitt, C. A. (2005) · Nature

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Senescence-associated reprogramming promotes cancer stemness

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Telomeres, Telomerase, and SenescenceCancer Cells and Metastasis

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Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

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Telomeres, Telomerase, and SenescenceCancer, Hypoxia, and Metabolism

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Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma

Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Köchert, K., Bouhlel, M. A., Richter, J., Soler, E., et al. (2010) · Nature Medicine

Genomics and Chromatin DynamicsLymphoma Diagnosis and Treatment

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Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma

Rahal, R., Frick, M., Romero, R., Korn, J. M., Kridel, R., Chun Chan, F., Meissner, B., Bhang, H.-E., Ruddy, D., Kauffmann, A., et al. (2014) · Nature Medicine

Lymphoma Diagnosis and TreatmentNF-κB Signaling Pathways

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Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis

Arends, C. M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., et al. (2018) · Leukemia

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

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Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphomagenesis via Suv39h1-Dependent Senescence

Reimann, M., Lee, S., Loddenkemper, C., Dörr, J. R., Tabor, V., Aichele, P., Stein, H., Dörken, B., Jenuwein, T., & Schmitt, C. A. (2010) · Cancer Cell

Telomeres, Telomerase, and SenescenceTGF-β signaling in diseases

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

Yu, Y., Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M. R., Qutob, N., van Rooijen, E., Werner-Klein, M., et al. (2018) · Cancer Cell

Melanoma and MAPK PathwaysEpigenetics and DNA Methylation

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Cellular senescence predicts treatment outcome in metastasised colorectal cancer

Haugstetter, A. M., Loddenkemper, C., Lenze, D., Gröne, J., Standfuß, C., Petersen, I., Dörken, B., & Schmitt, C. A. (2010) · British Journal of Cancer

Telomeres, Telomerase, and SenescenceColorectal Cancer Treatments and Studies

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

Yu, Y., Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M. R., Qutob, N., van Rooijen, E., Werner-Klein, M., et al. (2018) · Cancer Cell

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

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