Chavakis, Triantafyllos

Defining trained immunity and its role in health and disease

Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., et al. (2020) · Nature Reviews Immunology

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 2,690

Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

Hajishengallis, G., & Chavakis, T. (2021) · Nature Reviews Immunology

Oral microbiology and periodontitis researchDental Research and COVID-19

Cited by 1,871

Understanding RAGE, the receptor for advanced glycation end products

Bierhaus, A., Humpert, P. M., Morcos, M., Wendt, T., Chavakis, T., Arnold, B., Stern, D. M., & Nawroth, P. P. (2005) · Journal of Molecular Medicine

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 1,297

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Mitroulis, I., Ruppova, K., Wang, B., Chen, L.-S., Grzybek, M., Grinenko, T., Eugster, A., Troullinaki, M., Palladini, A., Kourtzelis, I., et al. (2018) · Cell

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 1,100

Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

Kalafati, L., Kourtzelis, I., Schulte-Schrepping, J., Li, X., Hatzioannou, A., Grinenko, T., Hagag, E., Sinha, A., Has, C., Dietz, S., et al. (2020) · Cell

Immune responses and vaccinationsImmune cells in cancer

Cited by 648

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

Eskan, M. A., Jotwani, R., Abe, T., Chmelar, J., Lim, J.-H., Liang, S., Ciero, P. A., Krauss, J. L., Li, F., Rauner, M., et al. (2012) · Nature Immunology

Oral microbiology and periodontitis researchCell Adhesion Molecules Research

Cited by 429

Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

Graessler, J., Qin, Y., Zhong, H., Zhang, J., Licinio, J., Wong, M.-L., Xu, A., Chavakis, T., Bornstein, A. B., Ehrhart-Bornstein, M., et al. (2013) · The Pharmacogenomics Journal

Gut microbiota and healthBariatric Surgery and Outcomes

Cited by 428

Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes

Chavakis, T., Hussain, M., Kanse, S. M., Peters, G., Bretzel, R. G., Flock, J.-I., Herrmann, M., & Preissner, K. T. (2002) · Nature Medicine

Antimicrobial Resistance in StaphylococcusCell Adhesion Molecules Research

Cited by 264

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

Teufel, A., Itzel, T., Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schönfels, W., Herrmann, A., Brückner, S., Stickel, F., et al. (2016) · Gastroenterology

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 229

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

Akoumianaki, T., Kyrmizi, I., Valsecchi, I., Gresnigt, M. S., Samonis, G., Drakos, E., Boumpas, D., Muszkieta, L., Prevost, M.-C., Kontoyiannis, D. P., et al. (2016) · Cell Host & Microbe

Autophagy in Disease and TherapyAntifungal resistance and susceptibility

Cited by 218

Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis

Langer, H. F., Chung, K.-J., Orlova, V. V., Choi, E. Y., Kaul, S., Kruhlak, M. J., Alatsatianos, M., DeAngelis, R. A., Roche, P. A., Magotti, P., et al. (2010) · Blood

Complement system in diseasesAngiogenesis and VEGF in Cancer

Cited by 176

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity

Chung, K.-J., Chatzigeorgiou, A., Economopoulou, M., Garcia-Martin, R., Alexaki, V. I., Mitroulis, I., Nati, M., Gebler, J., Ziemssen, T., Goelz, S. E., et al. (2017) · Nature Immunology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 175

Loss of hepatic Mboat7 leads to liver fibrosis

Thangapandi, V. R., Knittelfelder, O., Brosch, M., Patsenker, E., Vvedenskaya, O., Buch, S., Hinz, S., Hendricks, A., Nati, M., Herrmann, A., et al. (2021) · Gut

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 125

Vascular Endothelial Growth Factor (VEGF)-induced Up-regulation of CCN1 in Osteoblasts Mediates Proangiogenic Activities in Endothelial Cells and Promotes Fracture Healing

Athanasopoulos, A. N., Schneider, D., Keiper, T., Alt, V., Pendurthi, U. R., Liegibel, U. M., Sommer, U., Nawroth, P. P., Kasperk, C., & Chavakis, T. (2007) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchAngiogenesis and VEGF in Cancer

Cited by 99

The Multifaceted Roles of Macrophages in NAFLD Pathogenesis

Vonderlin, J., Chavakis, T., Sieweke, M., & Tacke, F. (2023) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 96

Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation

Kanczkowski, W., Alexaki, V.-I., Tran, N., Großklaus, S., Zacharowski, K., Martinez, A., Popovics, P., Block, N. L., Chavakis, T., Schally, A. V., et al. (2013) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 90

Adipocyte-specific hypoxia-inducible factor 2α deficiency exacerbates obesity-induced brown adipose tissue dysfunction and metabolic dysregulation

García-Martín, R., Alexaki, V. I., Qin, N., Rubín de Celis, M. F., Economopoulou, M., Ziogas, A., Gercken, B., Kotlabova, K., Phieler, J., Ehrhart-Bornstein, M., et al. (2016) · Molecular and Cellular Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 86