Sproul, Duncan

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M.-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., et al. (2020) · Nature Genetics

interferon and immune responsesInflammasome and immune disorders

Cited by 192

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

Sproul, D., Kitchen, R. R., Nestor, C. E., Dixon, J. M., Sims, A. H., Harrison, D. J., Ramsahoye, B. H., & Meehan, R. R. (2012) · Genome Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 191

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

Sproul, D., Nestor, C., Culley, J., Dickson, J. H., Dixon, J. M., Harrison, D. J., Meehan, R. R., Sims, A. H., & Ramsahoye, B. H. (2011) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 159

An epigenetic predictor of death captures multi-modal measures of brain health

Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., et al. (2021) · Molecular Psychiatry

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 139

A Functional Genetic Atlas of Parkin Resolves Variants of Uncertain Significance and Predicts Parkinson’s Disease Age at Onset

Aslanzadeh, V., Glendinning, S., Sari, Y., Clarke, M., Rodger, C. J., Lin, X., Lenka, D. R., Richardson, L., Liang, J. R., Kleinz, T., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Parkinson's Disease Mechanisms and TreatmentsGenomics and Rare Diseases

Cited by 1