Turkson, James

STATs in oncogenesis

Bowman, T., Garcia, R., Turkson, J., & Jove, R. (2000) · Oncogene

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 1,743

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Catlett-Falcone, R., Landowski, T. H., Oshiro, M. M., Turkson, J., Levitzki, A., Savino, R., Ciliberto, G., Moscinski, L., Fernández-Luna, J. L., Nuñez, G., et al. (1999) · Immunity

Cytokine Signaling Pathways and InteractionsMultiple Myeloma Research and Treatments

Cited by 1,638

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Niu, G., Wright, K. L., Huang, M., Song, L., Haura, E., Turkson, J., Zhang, S., Wang, T., Sinibaldi, D., Coppola, D., et al. (2002) · Oncogene

Angiogenesis and VEGF in CancerCytokine Signaling Pathways and Interactions

Cited by 1,207

Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation

Turkson, J., Bowman, T., Garcia, R., Caldenhoven, E., De Groot, R. P., & Jove, R. (1998) · Molecular and Cellular Biology

Cytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 651

STAT proteins: novel molecular targets for cancer drug discovery

Turkson, J., & Jove, R. (2000) · Oncogene

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 643

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

Epling-Burnette, P. K., Liu, J. H., Catlett-Falcone, R., Turkson, J., Oshiro, M., Kothapalli, R., Li, Y., Wang, J.-M., Yang-Yen, H.-F., Karras, J., et al. (2001) · Journal of Clinical Investigation

Cytokine Signaling Pathways and InteractionsCell death mechanisms and regulation

Cited by 633

Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

Gritsko, T., Williams, A., Turkson, J., Kaneko, S., Bowman, T., Huang, M., Nam, S., Eweis, I., Diaz, N., Sullivan, D., et al. (2006) · Clinical Cancer Research

Cytokine Signaling Pathways and InteractionsCell death mechanisms and regulation

Cited by 563

Stat3 controls lysosomal-mediated cell death in vivo

Kreuzaler, P. A., Staniszewska, A. D., Li, W., Omidvar, N., Kedjouar, B., Turkson, J., Poli, V., Flavell, R. A., Clarkson, R. W. E., & Watson, C. J. (2011) · Nature Cell Biology

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 312

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity

Turkson, J., Zhang, S., Palmer, J., Kay, H., Stanko, J., Mora, L. B., Sebti, S., Yu, H., & Jove, R. (2004) · Molecular Cancer Therapeutics

Metal complexes synthesis and propertiesCytokine Signaling Pathways and Interactions

Cited by 188

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

Zhang, X., Yue, P., Fletcher, S., Zhao, W., Gunning, P. T., & Turkson, J. (2010) · Biochemical Pharmacology

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 179

Constitutively active Stat3 enhances neu-mediated migration and metastasis in mammary tumors via upregulation of Cten

Barbieri, I., Pensa, S., Pannellini, T., Quaglino, E., Maritano, D., Demaria, M., Voster, A., Turkson, J., Cavallo, F., Watson, C. J., et al. (2010) · Cancer Research

Cytokine Signaling Pathways and InteractionsMechanisms of cancer metastasis

Cited by 148