Grün, Dominic

Combinatorial microRNA target predictions

Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 4,603

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Masuda, T., Sankowski, R., Staszewski, O., Böttcher, C., Amann, L., Sagar, Scheiwe, C., Nessler, S., Kunz, P., van Loo, G., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,310

Single-cell messenger RNA sequencing reveals rare intestinal cell types

Grün, D., Lyubimova, A., Kester, L., Wiebrands, K., Basak, O., Sasaki, N., Clevers, H., & van Oudenaarden, A. (2015) · Nature

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,234

A human liver cell atlas reveals heterogeneity and epithelial progenitors

Aizarani, N., Saviano, A., Sagar, Mailly, L., Durand, S., Herman, J. S., Pessaux, P., Baumert, T. F., & Grün, D. (2019) · Nature

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 1,147

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

Jordão, M. J. C., Sankowski, R., Brendecke, S. M., Sagar, Locatelli, G., Tai, Y.-H., Tay, T. L., Schramm, E., Armbruster, S., Hagemeyer, N., et al. (2019) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 843

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, M., Menon, V., Habib, N., Taga, M. F., Ma, Y., Yung, C. J., Cimpean, M., Khairallah, A., Coronas-Samano, G., Sankowski, R., et al. (2020) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 722

Validation of noise models for single-cell transcriptomics

Grün, D., Kester, L., & van Oudenaarden, A. (2014) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 721

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

Tay, T. L., Mai, D., Dautzenberg, J., Fernández-Klett, F., Lin, G., Sagar, Datta, M., Drougard, A., Stempfl, T., Ardura-Fabregat, A., et al. (2017) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 597

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

Grün, D., Muraro, M. J., Boisset, J.-C., Wiebrands, K., Lyubimova, A., Dharmadhikari, G., van den Born, M., van Es, J., Jansen, E., Clevers, H., et al. (2016) · Cell Stem Cell

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 586

Design and Analysis of Single-Cell Sequencing Experiments

Grün, D., & van Oudenaarden, A. (2015) · Cell

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 536

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects

Mereu, E., Lafzi, A., Moutinho, C., Ziegenhain, C., McCarthy, D. J., Álvarez-Varela, A., Batlle, E., Sagar, Grün, D., Lau, J. K., et al. (2020) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 499

Mapping microglia states in the human brain through the integration of high-dimensional techniques

Sankowski, R., Böttcher, C., Masuda, T., Geirsdottir, L., Sagar, Sindram, E., Seredenina, T., Muhs, A., Scheiwe, C., Shah, M. J., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 449

FateID infers cell fate bias in multipotent progenitors from single-cell RNA-seq data

Herman, J. S., Sagar, & Grün, D. (2018) · Nature Methods

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 363

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

Marsee, A., Roos, F. J. M., Verstegen, M. M. A., Marsee, A., Roos, F., Verstegen, M., Clevers, H., Vallier, L., Takebe, T., Huch, M., et al. (2021) · Cell Stem Cell

3D Printing in Biomedical ResearchPancreatic function and diabetes

Cited by 310

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

Lu, T. T.-H., Heyne, S., Dror, E., Casas, E., Leonhardt, L., Boenke, T., Yang, C.-H., Sagar, Arrigoni, L., Dalgaard, K., et al. (2018) · Cell Metabolism

Pancreatic function and diabetesEpigenetics and DNA Methylation

Cited by 151

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Masuda, T., Sankowski, R., Staszewski, O., Böttcher, C., Amann, L., Sagar, Scheiwe, C., Nessler, S., Kunz, P., van Loo, G., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 26