Tran, John C.

Mapping intact protein isoforms in discovery mode using top-down proteomics

Tran, J. C., Zamdborg, L., Ahlf, D. R., Lee, J. E., Catherman, A. D., Durbin, K. R., Tipton, J. D., Vellaichamy, A., Kellie, J. F., Li, M., et al. (2011) · Nature

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 665

Gel-Eluted Liquid Fraction Entrapment Electrophoresis: An Electrophoretic Method for Broad Molecular Weight Range Proteome Separation

Tran, J. C., & Doucette, A. A. (2008) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMicrofluidic and Capillary Electrophoresis Applications

Cited by 206

Large-scale Top-down Proteomics of the Human Proteome: Membrane Proteins, Mitochondria, and Senescence

Catherman, A. D., Durbin, K. R., Ahlf, D. R., Early, B. P., Fellers, R. T., Tran, J. C., Thomas, P. M., & Kelleher, N. L. (2013) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 157

The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput

Kellie, J. F., Tran, J. C., Lee, J. E., Ahlf, D. R., Thomas, H. M., Ntai, I., Catherman, A. D., Durbin, K. R., Zamdborg, L., Vellaichamy, A., et al. (2010) · Molecular BioSystems

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 99

Optimizing capillary electrophoresis for top‐down proteomics of 30–80 kDa proteins

Li, Y., Compton, P. D., Tran, J. C., Ntai, I., & Kelleher, N. L. (2014) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsMicrofluidic and Capillary Electrophoresis Applications

Cited by 95

Evaluation of the Compact High-Field Orbitrap for Top-Down Proteomics of Human Cells

Ahlf, D. R., Compton, P. D., Tran, J. C., Early, B. P., Thomas, P. M., & Kelleher, N. L. (2012) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 89

High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry

Sawyer, W. S., Srikumar, N., Carver, J., Chu, P. Y., Shen, A., Xu, A., Williams, A. J., Spiess, C., Wu, C., Liu, Y., et al. (2020) · Proceedings of the National Academy of Sciences

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 55

Assessment of KRAS G12C Target Engagement by a Covalent Inhibitor in Tumor Biopsies Using an Ultra-Sensitive Immunoaffinity 2D-LC–MS/MS Approach

Meng, L., Chan, E. W., Ng, C., Aimi, J., Tran, J. C., Oh, A. J., Merchant, M., Purkey, H. E., Heffron, T. P., Kaur, S., et al. (2022) · Analytical Chemistry

Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations

Cited by 15