Takano, Takahiro

Sleep Drives Metabolite Clearance from the Adult Brain

Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., O’Donnell, J., Christensen, D. J., Nicholson, C., Iliff, J. J., et al. (2013) · Science

Sleep and Wakefulness ResearchCerebrospinal fluid and hydrocephalus

Cited by 5,411

Uniquely Hominid Features of Adult Human Astrocytes

Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,488

An astrocytic basis of epilepsy

Tian, G.-F., Azmi, H., Takano, T., Xu, Q., Peng, W., Lin, J., Oberheim, N., Lou, N., Wang, X., Zielke, H. R., et al. (2005) · Nature Medicine

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 806

Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo

Wang, X., Lou, N., Xu, Q., Tian, G.-F., Peng, W. G., Han, X., Kang, J., Takano, T., & Nedergaard, M. (2006) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 685

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

Han, X., Chen, M., Wang, F., Windrem, M., Wang, S., Shanz, S., Xu, Q., Oberheim, N. A., Bekar, L., Betstadt, S., et al. (2013) · Cell Stem Cell

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 635

Signaling at the Gliovascular Interface

Simard, M., Arcuino, G., Takano, T., Liu, Q. S., & Nedergaard, M. (2003) · The Journal of Neuroscience

Barrier Structure and Function StudiesConnexins and lens biology

Cited by 586

Cortical spreading depression causes and coincides with tissue hypoxia

Takano, T., Tian, G.-F., Peng, W., Lou, N., Lovatt, D., Hansen, A. J., Kasischke, K. A., & Nedergaard, M. (2007) · Nature Neuroscience

Migraine and Headache StudiesTraumatic Brain Injury and Neurovascular Disturbances

Cited by 472

Beyond the role of glutamate as a neurotransmitter

Nedergaard, M., Takano, T., & Hansen, A. J. (2002) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 450

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, M., et al. (2015) · Nature Communications

Neuroscience and Neuropharmacology ResearchAdvanced MRI Techniques and Applications

Cited by 381

Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier

Lou, N., Takano, T., Pei, Y., Xavier, A. L., Goldman, S. A., & Nedergaard, M. (2016) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 364

Loss of astrocytic domain organization in the epileptic brain

Oberheim, N. A., Tian, G.-F., Han, X., Peng, W., Takano, T., Ransom, B., & Nedergaard, M. (2008) · The Journal of Neuroscience

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 303

Critical role of aquaporin-4 (AQP4) in astrocytic Ca 2+ signaling events elicited by cerebral edema

Thrane, A. S., Rappold, P. M., Fujita, T., Torres, A., Bekar, L. K., Takano, T., Peng, W., Wang, F., Rangroo Thrane, V., Enger, R., et al. (2011) · Proceedings of the National Academy of Sciences

Ion Transport and Channel RegulationCerebrospinal fluid and hydrocephalus

Cited by 254

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

Fujita, T., Chen, M. J., Li, B., Smith, N. A., Peng, W., Sun, W., Toner, M. J., Kress, B. T., Wang, L., Benraiss, A., et al. (2014) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 141